| Type | Description |
|---|---|
| Definition | checkpoint with forkhead and ring finger domains |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:30:00 | Circ_CHFR expedites cell growth, migration and inflammation in ox-LDL-treated human vascular smooth muscle cells via the miR-214-3p/Wnt3/beta-catenin pathway. | 32271446 |
| 2019-04-20 10:32:00 | Lower CHFR expression was independently associated with unfavorable prognosis in acute myeloid leukemia. Moreover, aberrant CHFR promoter methylation was a rare event in myeloid malignances. | 29115660 |
| 2019-03-16 10:25:00 | The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying HDAC1 as a molecular target in controlling NANOGHIGH immune-refractory cancer. | 30060952 |
| 2019-02-16 12:04:00 | These data suggest that CHFR methylation may be associated with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. | 30562637 |
| 2018-05-26 11:47:00 | JNK inhibitor prevents SIRT1 phosphorylation, leading to elevated SIRT1 protein levels even in the presence of H2O2. Taken together, our results indicate that CHFR plays a crucial role in the cellular stress response pathway by controlling the stability and function of SIRT1. | 27883020 |
| Type | IDs |
|---|---|
| Synonymous | RNF116, RNF196 |
| Gene |
UniProtKB-ID:
CHFR_HUMAN
UniprotKB:
Q96EP1
UniParc:
UPI0000236D67,
UPI0001A59586,
UPI0001A59587,
UPI000006FA02,
UPI000006CD0B
EMBL:
AC127070,
AK302785,
BC012072,
AL137561,
AK027687,
AF170724,
AK304333,
AK001658
Ensembl:
ENSG00000072609
KO:
hsa:55743
|
| Nucleutide sequences |
EMBL-CDS:
AAF91084.1,
BAA91817.1,
BAG65178.1,
AAH12072.1,
BAB55297.1,
BAG63989.1,
CAB70812.1
Ensembl_TRS:
ENST00000450056,
ENST00000432561,
ENST00000266880,
ENST00000443047
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000416431,
ENSP00000392395,
ENSP00000398735,
ENSP00000266880
RefSeq:
NP_001154818.1,
NP_060693.2,
NP_001154819.1,
NP_001154817.1,
NP_001154816.1
|
| Others |
UniRef100:
UniRef100_Q96EP1
UniRef90:
UniRef90_Q96EP1
UniRef50:
UniRef50_Q96EP1
UniGene:
Hs.720197
CCDS:
CCDS53847.1,
CCDS53849.1,
CCDS53848.1,
CCDS31937.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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