| Type | Description |
|---|---|
| Definition | parvin alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:57:00 | A novel signaling pathway consisting of alpha-parvin, G3BP2, and TWIST1 regulates breast cancer progression and metastasis, this suggests that the activation of this signaling pathway is a key factor for driving the progression and poor clinical outcome of human ER-negative breast cancer. | 30804457 |
| 2018-09-22 10:41:00 | edited form of miR-378a-3p preferentially binds to the 3'-UTR of the PARVA oncogene and inhibits its expression, thus preventing the progression of melanoma towards the malignant phenotype | 29386624 |
| 2016-04-30 12:03:00 | Protein expression of alpha-Parvin increases with colorectal cancer progression. | 26115385 |
| 2016-01-23 11:03:00 | PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma | 25738875 |
| 2015-08-29 10:19:00 | alpha-pv-deficient HUVECs show reduced stable adherens junctions, decreased monolayer formation, and impaired motility, associated with reduced formation of integrin-mediated cell-extracellular matrix adhesion structures and an altered actin cytoskeleton. | 25925587 |
| Type | IDs |
|---|---|
| Synonymous | CH-ILKBP, MXRA2 |
| Gene |
UniProtKB-ID:
PARVA_HUMAN
UniprotKB:
Q9NVD7
UniParc:
UPI0000035879,
UPI0000070275
EMBL:
AF237771,
AK001655,
BC016713,
AF325830,
AK022316,
BC014535
Ensembl:
ENSG00000197702
KO:
hsa:55742
|
| Nucleutide sequences |
EMBL-CDS:
AAH16713.1,
BAB14009.1,
BAA91815.1,
AAK49911.1,
AAH14535.1,
AAG27173.1
Ensembl_TRS:
ENST00000334956
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000334008
RefSeq:
XP_005253072.1,
NP_060692.3
|
| Others |
UniRef100:
UniRef100_Q9NVD7
UniRef90:
UniRef90_Q9NVD7
UniRef50:
UniRef50_Q9NVD7
UniGene:
Hs.432914
CCDS:
CCDS44541.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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