| Type | Description |
|---|---|
| Definition | ER degradation enhancing alpha-mannosidase like protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:10:00 | EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD. | 32065582 |
| 2020-08-13 18:51:00 | A novel gene in early childhood diabetes: EDEM2 silencing decreases SLC2A2 and PXD1 expression, leading to impaired insulin secretion. | 32556999 |
| 2015-06-20 11:03:00 | EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog | 24910992 |
| 2014-10-11 12:25:00 | Glycoproteins mannose trimming from Man9GlcNAc2 to Man8GlcNAc2 is conducted mainly by EDEM2. | 25092655 |
| 2010-09-15 22:05:00 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 20802025 |
| Type | IDs |
|---|---|
| Synonymous | C20orf31, C20orf49, bA4204.1 |
| Gene |
UniProtKB-ID:
EDEM2_HUMAN
UniprotKB:
Q9BV94
UniParc:
UPI00004E1937,
UPI00001285D9
EMBL:
AK300212,
AK001645,
AY358580,
AL356652,
CH471077,
AK023931,
AL135844,
BC001371,
BC016184,
CR457266
Ensembl:
ENSG00000088298
KO:
hsa:55741
|
| Nucleutide sequences |
EMBL-CDS:
AAH01371.1,
BAB14731.1,
BAA91806.1,
CAG33547.1,
EAW76228.1,
AAQ88943.1,
BAG61981.1,
AAH16184.1
Gene_ORFName:
UNQ573/PRO1135
Ensembl_TRS:
ENST00000374491,
ENST00000374492
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363616,
ENSP00000363615
RefSeq:
NP_060687.2,
NP_001138497.1
|
| Others |
UniRef100:
UniRef100_Q9BV94
UniRef90:
UniRef90_Q9BV94
UniRef50:
UniRef50_Q9BV94
UniGene:
Hs.720177
CCDS:
CCDS13247.1,
CCDS46592.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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