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55738 ARFGAP1

55738

ARFGAP1

ADP ribosylation factor GTPase activating protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition ADP ribosylation factor GTPase activating protein 1

研究结论

Date Results Publications
2019-01-05 11:39:00 ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton. 29141986
2015-07-25 11:13:00 ARFGAP1 is found associated with lipid droplets at steady state in some but not all hepatocytes. 25397679
2014-07-05 10:06:00 ARFGAP1 is a host factor for Hepatitis C Virus RNA replication, and is hijacked by HCV NS5A to remove COPI cargo Sac1 from the site of HCV replication to maintain high levels of PI4P. 24623438
2012-05-05 10:03:00 ArfGAP1 is identified as the first GTPase activating protein (GAP) for leucine-rich repeat kinase 2 (LRRK2). 22423108
2011-07-16 11:17:00 role of ARFGAP1 in AP-2-regulated endocytosis has mechanistic parallels with its roles in COPI transport, as both its GAP activity and coat function contribute to promoting AP-2 transport 21499258

名称对应

Type IDs
Synonymous ARF1GAP, HRIHFB2281
Gene
UniProtKB-ID: ARFG1_HUMAN, Q53F62_HUMAN
UniprotKB: Q8N6T3, Q53F62
UniParc: UPI000002A3F2, UPI0000350794, UPI0001E8EF30, UPI0000125DED, UPI000191507B, UPI000050A9B0
EMBL: AK296351, BC011876, AK223427, CH471077, AK027268, AB015340, AK027441, AK001629, AL121827, BC006085, BC000786, BC028233, AL137744, AK303454
Ensembl: ENSG00000101199
KO: hsa:55738
Nucleutide sequences
EMBL-CDS: AAH11876.1, AAH06085.1, EAW75292.1, BAA91796.1, AAH28233.1, CAB70901.1, BAB55113.1, AAH00786.1, EAW75294.1, BAB55009.1, BAA88117.1, BAH13964.1, BAH12326.1, BAD97147.1
Ensembl_TRS: ENST00000370275, ENST00000370283, ENST00000519604, ENST00000519273, ENST00000353546
Protein sequencees
Ensembl_PRO: ENSP00000443716, ENSP00000314615, ENSP00000359306, ENSP00000359298, ENSP00000430500
RefSeq: NP_001268413.1, NP_001268411.1, XP_016883439.1, NP_783202.1, NP_060679.1, NP_001268412.1, XP_011527203.1, XP_006723886.1
Others
UniRef100: UniRef100_Q53F62, UniRef100_Q8N6T3
UniRef90: UniRef90_Q8N6T3
UniRef50: UniRef50_Q8N6T3
UniGene: Hs.25584
CCDS: CCDS13516.1, CCDS63328.1, CCDS63327.1, CCDS13515.1, CCDS63326.1

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