| Type | Description |
|---|---|
| Definition | anti-silencing function 1B histone chaperone |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:39:00 | ASF1B overexpression significantly enhanced the proliferation and migration of clear cell renal cell carcinomacells, while silencing ASF1B expression significantly inhibited the proliferation and migration. ASF1B overexpression promoted tumor cell proliferation and migration, which was dependent on the AKT/P70 S6K1 pathway. | 30777326 |
| 2019-03-30 12:59:00 | ASF1B is highly expressed in the prostate cancer tissues and cells.ASF1B regulatres the PI3K/Akt signaling pathway in prostate cancer. | 30132513 |
| 2017-06-24 10:16:00 | histone binding to ASF1B is required for the induction of beta-cell proliferation. | 27753532 |
| 2014-12-06 12:01:00 | Data indicate Tousled-like kinases (TLK1) phosphorylation has an impact on cell cycle proteins Asf1a and Asf1b function. | 24598821 |
| 2014-04-19 10:30:00 | Co-depletion of the histone chaperones ASF1a and ASF1b in human cells induces all hallmarks of alternative lengthening of telomeres in both primary and cancer cells. | 24413054 |
| Type | IDs |
|---|---|
| Synonymous | CIA-II |
| Gene |
UniProtKB-ID:
ASF1B_HUMAN,
A0A024R7G4_HUMAN
UniprotKB:
Q9NVP2,
A0A024R7G4
UniParc:
UPI00000437D4
EMBL:
AC022098,
AK001288,
AK001466,
BC007726,
AF279307,
AK223080,
CH471106,
CR457235,
BC036521,
AB104486,
BC010014
Ensembl:
ENSG00000288210,
ENSG00000105011
KO:
hsa:55723
|
| Nucleutide sequences |
EMBL-CDS:
CAG33516.1,
AAH36521.1,
BAA91602.1,
AAH07726.1,
BAD96800.1,
AAH10014.1,
BAC87709.1,
AAK82973.1,
BAA91708.1,
EAW84401.1,
EAW84402.1
Gene_ORFName:
hCG_27531
Ensembl_TRS:
ENST00000263382,
ENST00000672225
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263382,
ENSP00000499863
RefSeq:
NP_060624.1
|
| Others |
UniRef100:
UniRef100_Q9NVP2
UniRef90:
UniRef90_Q9NVP2
UniRef50:
UniRef50_Q9Y294
UniGene:
Hs.26516
CCDS:
CCDS12306.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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