| Type | Description |
|---|---|
| Definition | docking protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:33:00 | Study of DOK4 gene expression and promoter methylation in sporadic breast cancer. | 32386480 |
| 2013-03-02 13:17:00 | the current study have explored in more detail the structure and function of the Dok-4 PTB domain. | 22982678 |
| 2010-01-21 00:00:00 | IRS-5 (DOK4) is significantly upregulated in 90% of examined clear cell RCCs. Studies on this gene has shown that it is regulated through chromatin remodeling in kidney cells | 17443497 |
| 2010-01-21 00:00:00 | DOK4 expression in human T cells has been demonstrated, and its genomic structure has been predicted. | 12595900 |
| 2010-01-21 00:00:00 | Results suggest that Dok-4, through activation of the Rap1-ERK1/2 pathway, regulates GDNF-mediated neurite outgrowth during neuronal development. | 16820412 |
| Type | IDs |
|---|---|
| Synonymous | IRS-5, IRS5 |
| Gene |
UniProtKB-ID:
DOK4_HUMAN,
H3BQ19_HUMAN,
A0A024R6S2_HUMAN
UniprotKB:
Q8TEW6,
H3BQ19,
A0A024R6S2
UniParc:
UPI0000D9F15E,
UPI0000070AA4
EMBL:
AF466369,
CH471092,
BC003541,
BC001540,
AC004382,
AC009052,
AK001350
Ensembl:
ENSG00000125170
KO:
hsa:55715
|
| Nucleutide sequences |
EMBL-CDS:
AAL74195.1,
BAA91642.1,
AAH03541.1,
AAC24310.1,
AAH01540.1,
EAW82934.1,
EAW82932.1,
EAW82933.1
Gene_ORFName:
hCG_16489
Ensembl_TRS:
ENST00000569548,
ENST00000340099,
ENST00000566936
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344277,
ENSP00000455128,
ENSP00000455566
RefSeq:
XP_024306115.1,
XP_024306116.1,
NP_060580.2,
NP_001356549.1,
NP_001356548.1,
NP_001356550.1,
NP_001317485.1,
NP_001356547.1
|
| Others |
UniRef100:
UniRef100_H3BQ19,
UniRef100_Q8TEW6
UniRef90:
UniRef90_A0A2K5HW96,
UniRef90_Q8TEW6
UniRef50:
UniRef50_Q8TEW6
UniGene:
Hs.279832
CCDS:
CCDS10783.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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