| Type | Description |
|---|---|
| Definition | kelch repeat and BTB domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:49:00 | Our findings suggest that KBTBD4 mutations are uncommon in Brazilian MBGRP3 and MBGRP4 medulloblastomas subgroups. | 31403685 |
| Type | IDs |
|---|---|
| Synonymous | BKLHD4, HSPC252 |
| Gene |
UniProtKB-ID:
KBTB4_HUMAN,
A0A075B6T4_HUMAN
UniprotKB:
Q9NVX7,
A0A075B6T4
UniParc:
UPI0000D4DDB6,
UPI00001FA13D,
UPI000007169E
EMBL:
BC002736,
AK001749,
KF459542,
AC104942,
CR457270,
AK001312,
AL713735,
CH471064
Ensembl:
ENSG00000284900,
ENSG00000123444
KO:
hsa:55709
|
| Nucleutide sequences |
EMBL-CDS:
EAW67902.1,
EAW67898.1,
CAD28521.1,
AAH02736.1,
BAA91616.1,
BAA91880.1,
EAW67900.1,
EAW67899.1,
EAW67901.1,
CAG33551.1
Ensembl_TRS:
ENST00000647201,
ENST00000646317,
ENST00000430070,
ENST00000395288,
ENST00000526005,
ENST00000645388,
ENST00000533290
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000433340,
ENSP00000378703,
ENSP00000495324,
ENSP00000415106,
ENSP00000495892,
ENSP00000495796,
ENSP00000436713
RefSeq:
NP_001305645.1,
NP_001305646.1,
XP_016873498.1,
NP_001305649.1,
NP_001305651.1,
NP_001305650.1,
NP_001305652.1,
NP_057590.3,
NP_001305647.1,
NP_060565.4,
NP_001305648.1,
NP_001305654.1,
NP_001305653.1
|
| Others |
UniRef100:
UniRef100_A0A075B6T4,
UniRef100_Q9NVX7
UniRef90:
UniRef90_Q9NVX7
UniRef50:
UniRef50_Q9NVX7
UniGene:
Hs.718483
CCDS:
CCDS7940.1,
CCDS44594.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31391242 |
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. J Cell Sci Marcel Nowak , Benjamin Suenkel , Pablo Porras , Rebekka Migotti , Franziska Schmidt , Melanie Kny , Xiaoxi Zhu , Erich E Wanker , Gunnar Dittmar , Jens Fielitz , Thomas Sommer |
2019-09-06 | - |
| 31403685 |
Lack of KBTBD4 Mutations in Molecularly Classified Brazilian Medulloblastomas. J. Neuropathol. Exp. Neurol. LetÃcia Ferro Leal , Rodrigo de Oliveira Cavagna , Nathalia Cristina Campanella , Bruna Mançano , Gisele Caravina Almeida , Marcus Matsushita , Carlos Roberto Almeida Junior , Fabiano Saggioro , João Norberto Stavale , Suzana M F Malheiros , Matheus Lima , Glaucia N M Hajj , Luciano Neder , Rui Manuel Reis |
2019-09-01 | - |
| 29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26561776 |
Free Radic. Biol. Med. Ivan Verrastro , Karina Tveen-Jensen , Rudiger Woscholski , Corinne M Spickett , Andrew R Pitt |
2016-01-01 |
TUBA1B,
TUBB4B,
MYL12A,
CFL1,
MTHFD2,
DBN1,
DDB1,
DSP,
EEF2,
RPL22L1,
TUBB,
FASN,
GPC4,
SETX,
MPRIP,
FLNB,
RPL13A,
POLDIP2,
MYOF,
GNAI1,
GNAI2,
GPC1,
SLC25A5,
GSTM2,
ANXA2,
HSD17B1,
DNAJA1,
HSPA8,
HSP90AB1,
HSPD1,
JUP,
ARF4,
LDHB,
LGALS1,
MYO1B,
MYH10,
MYO1C,
MYO1D,
RPL10A,
NME1,
ATP5A1,
PRDX1,
ATP5C1,
LIMA1,
SLC25A3,
PKM,
PLEC,
PELO,
PPL,
KBTBD4,
RCC2,
PTEN,
GNB4,
RPL7,
RPL12,
RPL13,
RPL27,
RPL27A,
RPL31,
RPL38,
RPLP0,
RPLP2,
RPS2,
RPS3,
RPS4X,
RPS6,
RPS9,
RPS13,
RPS15A,
RPS17,
RPS20,
RPS25,
RPS26,
RPS27,
RPS27A,
S100A8,
S100A9,
SDC1,
SDC4,
SDCBP,
SKP1,
NCF1,
SNTB2,
SPTAN1,
SPTBN1,
SSFA2,
SSR4,
TUFM,
TXN,
UTRN,
YES1,
CALM1,
DCAF11,
HIST1H2AB,
C16orf13,
RPL14,
RPL23,
AKAP12
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 22939624 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell Mikko Taipale , Irina Krykbaeva , Martina Koeva , Can Kayatekin , Kenneth D Westover , Georgios I Karras , Susan Lindquist |
2012-08-31 |
NR1H3,
TRIM10,
SGK2,
PREB,
CDK3,
TNK2,
CDK4,
CDK6,
CDK7,
CDK9,
LOC400927-CSNK1E,
PCGF3,
TESK2,
MERTK,
KAT5,
CEBPE,
NPRL2,
CAMKK2,
MAP3K2,
FASTK,
RCBTB2,
PIM2,
WWP1,
CHEK1,
CDC37,
MAP4K1,
IRAK3,
TP53RK,
STK38,
KLHL32,
KLHL29,
FBXO17,
CLK2,
CLK3,
FBXO27,
ASB17,
RNF19B,
ACVR1C,
GRK7,
MAP3K8,
ASB6,
MYO3B,
RAB40A,
CSF1R,
FBXL14,
CSNK1A1,
CSNK1E,
HIPK4,
PDIK1L,
KLHL23,
SH3RF2,
SGK223,
DAPK3,
DCLK2,
ZBTB49,
DLX6,
DMPK,
EGFR,
EPHA2,
EPHA1,
EPHA4,
EPHB1,
EPHB6,
ERBB2,
ERBB3,
ERBB4,
AKT2,
ESR1,
PTK2B,
FBXL13,
FER,
FES,
MAPK15,
FGFR1,
FGFR3,
FGR,
ICK,
TRIM32,
TCF25,
STK38L,
FOXM1,
MAST2,
PASK,
LARP4B,
FBXO28,
DTX4,
FLT4,
ZC3H7B,
FBXW11,
TRIM2,
SF3B3,
TSSK2,
SGK3,
ALK,
FRK,
ABL1,
FYN,
KLHL34,
FBXL2
|
| 21145461 |
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell Eric J Bennett , John Rush , Steven P Gygi , J Wade Harper |
2010-12-10 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 16169070 |
A human protein-protein interaction network: a resource for annotating the proteome. Cell Ulrich Stelzl , Uwe Worm , Maciej Lalowski , Christian Haenig , Felix H Brembeck , Heike Goehler , Martin Stroedicke , Martina Zenkner , Anke Schoenherr , Susanne Koeppen , Jan Timm , Sascha Mintzlaff , Claudia Abraham , Nicole Bock , Silvia Kietzmann , Astrid Goedde , Engin Toksöz , Anja Droege , Sylvia Krobitsch , Bernhard Korn , Walter Birchmeier , Hans Lehrach , Erich E Wanker |
2005-09-23 |
Eif4a2,
Tmsb4x,
Supt5,
Trp53,
Tuba1a,
Ppp2r2d,
Ilf2,
Fam101a,
Tubb2b,
Cggbp1,
Sh3d21,
Rab11b,
Dnaja2,
psmd14,
SRA1,
HDAC5,
PDCD6IP,
TOM1L1,
SH2D3C,
UBA2,
DNM1L,
COX17,
SCAMP2,
RWDD2B,
DPP3,
SNUPN,
TSSC4,
PDCD7,
CDH10,
PQBP1,
ARPC4,
ARPC3,
ACTR1B,
TOB1,
TRIM28,
RASA4,
PDZK1IP1,
SERF2,
RBM5,
TNK2,
TXNDC9,
CDK4,
PSME3,
MPHOSPH6,
NUTF2,
PATJ,
EIF1,
FLOT1,
PLIN3,
RASGRP2,
HNRNPR,
MRPS31,
GLYAT,
CDKN1A,
CDK2AP2,
RAMP3,
CDKN1B,
STUB1,
EFS,
SAP18,
PAK4,
DLEU1,
CDKN2B,
APBB3,
CDKN2C,
TFG,
NPM3,
HMG20B,
TUBB3,
TUBB4B,
CORO2B,
NDRG1,
MYL9,
RACK1,
NDC80,
WFDC2,
PRMT5,
ARIH2,
EMG1,
TIMM17A,
PPIE,
HAX1,
BAIAP2,
TADA3,
ATP5H,
EIF3M,
CEACAM5,
LRRC41,
VTI1B,
UNC13B,
DEAF1,
KAT5,
GLRX3,
DCTN2,
LAMTOR5,
PROCR,
AGR2,
CXCL13,
RABAC1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员