| Type | Description |
|---|---|
| Definition | NECAP endocytosis associated 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 10:34:00 | NECAP2 does not regulate the clathrin-mediated endocytosis of these cargos, the degradation of EGFR or the recycling of transferrin along the slow, Rab11-dependent recycling pathway. We show that protein knockdown of NECAP2 leads to enlarged early endosomes and causes the loss of the clathrin adapter AP-1 from the organelle. | 27206861 |
| 2009-02-18 09:00:00 | Describes identification and characterization of rat NECAP1 and NECAP2 and their roles in endocytosis. | 14555962 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NECP2_HUMAN,
B4DUR7_HUMAN
UniprotKB:
Q9NVZ3,
B4DUR7
UniParc:
UPI000013DEDA,
UPI0000072819,
UPI00017A7F97,
UPI000006F33F,
UPI0001948488
EMBL:
BC017014,
AK023545,
AK300764,
AL669962,
BC018914,
AK024468,
AK302227,
AL137802,
AK001282
Ensembl:
ENSG00000157191
KO:
hsa:55707
|
| Nucleutide sequences |
EMBL-CDS:
BAA91598.1,
BAB15758.1,
AAH17014.1,
BAG63581.1,
AAH18914.1,
BAB14605.1,
BAG62429.1
Ensembl_TRS:
ENST00000443980,
ENST00000457722,
ENST00000492095,
ENST00000337132
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000391942,
ENSP00000427620,
ENSP00000407091,
ENSP00000338746
RefSeq:
NP_001138750.1,
NP_001138749.1,
NP_060560.1,
XP_016857210.1,
XP_011540069.1
|
| Others |
UniRef100:
UniRef100_Q9NVZ3,
UniRef100_B4DUR7
UniRef90:
UniRef90_Q9NVZ3,
UniRef90_B4DUR7
UniRef50:
UniRef50_Q9NVZ3,
UniRef50_A0A2K5R1R5
UniGene:
Hs.437385
CCDS:
CCDS44066.1,
CCDS173.1,
CCDS44067.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31091453 |
Cell Rep Adnan Shami Shah , Alex G Batrouni , Dongsung Kim , Amith Punyala , Wendy Cao , Chun Han , Michael L Goldberg , Marcus B Smolka , Jeremy M Baskin |
2019-05-14 | - |
| 30463901 |
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression. Genes Dev. Lei Yu , Natee Jearawiriyapaisarn , Mary P Lee , Tomonori Hosoya , Qingqing Wu , Greggory Myers , Kim-Chew Lim , Ryo Kurita , Yukio Nakamura , Anne B Vojtek , Jean-François Rual , James Douglas Engel |
2018-12-01 | - |
| 29791485 |
PLoS ONE Sarah Ulbrich , Petra Janning , Ralf Seidel , Jakob Matschke , Anika Gonsberg , Sebastian Jung , Markus Glatzel , Martin Engelhard , Konstanze F Winklhofer , Jörg Tatzelt |
2018-01-01 | - |
| 28718761 |
The human cytoplasmic dynein interactome reveals novel activators of motility. Elife William B Redwine , Morgan E DeSantis , Ian Hollyer , Zaw Min Htet , Phuoc Tien Tran , Selene K Swanson , Laurence Florens , Michael P Washburn , Samara L Reck-Peterson |
2017-07-18 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27206861 |
NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. J. Cell. Sci. John P Chamberland , Lauren T Antonow , Michel Dias Santos , Brigitte Ritter |
2016-07-01 | - |
| 26638075 |
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell Gagan D Gupta , Ãtienne Coyaud , João Gonçalves , Bahareh A Mojarad , Yi Liu , Qianzhu Wu , Ladan Gheiratmand , David Comartin , Johnny M Tkach , Sally W T Cheung , Mikhail Bashkurov , Monica Hasegan , James D Knight , Zhen-Yuan Lin , Markus Schueler , Friedhelm Hildebrandt , Jason Moffat , Anne-Claude Gingras , Brian Raught , Laurence Pelletier |
2015-12-03 |
TANK,
SRA1,
LOC100129118,
TROAP,
PIGK,
WASH1,
DNAJB6,
LOC100506055,
TMEM35B,
OCLN,
LOC100507703,
ERVK3-1,
RBM14-RBM4,
COMMD3-BMI1,
UBA2,
SAE1,
ABCC5,
TIMM23B,
SCAMP2,
SCAMP3,
ARPC3,
ACTR3,
ACTR2,
NUBP2,
TSFM,
RAD50,
KIF20A,
PREB,
ACTR1B,
ACTR1A,
PDIA6,
BCAP31,
SUGP2,
CEBPZ,
ATP6AP2,
LPCAT3,
WASF2,
CDK2,
TENM1,
TXNDC9,
CDK4,
ALG3,
PRMT3,
PSME3,
MPHOSPH9,
CDK5,
TRIM13,
FLOT1,
PSMD14,
MFSD10,
STX6,
DCAF7,
STAM2,
ZMPSTE24,
STUB1,
SIGMAR1,
BET1,
DNAJA2,
PAK4,
KATNB1,
RTN3,
TNIP1,
EMC8,
CNPY2,
TFG,
TUBA1B,
TUBB4A,
TUBB4B,
NDRG1,
NDC80,
NSA2,
PGRMC2,
TUBGCP3,
SEC24B,
EMG1,
MCRS1,
TAB1,
BAIAP2,
PIBF1,
PPIH,
ZNHIT1,
PFDN6,
CLGN,
SLC25A17,
NXF1,
SEC23B,
SEC23A,
VAT1,
NCOA2,
HYOU1,
IPO8,
IPO7,
NEBL,
DCTN2,
PRDX4,
ARL6IP5,
AGPAT1,
RPP38,
CCT7
|
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24189400 |
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Mol. Syst. Biol. Jiannong Li , Keiryn Bennett , Alexey Stukalov , Bin Fang , Guolin Zhang , Takeshi Yoshida , Isamu Okamoto , Jae-Young Kim , Lanxi Song , Yun Bai , Xiaoning Qian , Bhupendra Rawal , Michael Schell , Florian Grebien , Georg Winter , Uwe Rix , Steven Eschrich , Jacques Colinge , John Koomen , Giulio Superti-Furga , Eric B Haura |
2013-01-01 |
CDH3,
DNAJB6,
AP1M2,
LRPPRC,
PDIA6,
CDK4,
CDK9,
DNAJA2,
TFG,
PKDREJ,
TUBA1B,
MYL12B,
BAIAP2,
DDX17,
MYL12A,
YWHAQ,
KDELR2,
CDC37,
ATXN2L,
PHB2,
CHUK,
FCHO2,
AP2M1,
AP2S1,
CLK3,
COL17A1,
S100A16,
HNRNPA1L2,
CSTA,
CTNNA1,
CTNNA2,
CTNNB1,
CTNND1,
EEF1A1P5,
AP2A1,
AP2A2,
AP1B1,
AP2B1,
DDX5,
DNAJB8,
DHCR7,
EEF1A1,
EEF1A2,
EGFR,
CTTN,
TUBB,
ANO5,
EPS15,
ERBB2,
ERBB3,
ESRRB,
EWSR1,
ACSL3,
HNRNPA3,
HIST1H2AA,
XRN2,
PHLDA1,
AAK1,
MRPS27,
VPS13A,
FUS,
SHC2,
ARMC8,
GAPDH,
GFAP,
RPS6KA6,
GNB1,
GNB2,
GNB3,
SFN,
GRB2,
GRB7,
MRPS28,
MRPS18B,
TIMM21,
SLC25A4,
SLC25A5,
SLC25A6,
GSTT1,
SEC61A1,
HIST1H1C,
HIST1H1D,
HIST1H1E,
HIST1H1T,
ANXA1,
ANXA2,
HIST1H1A,
HBA1,
HBB,
HBD,
HBE1,
HBG1,
HBG2,
HLA-A,
HLA-B,
HNRNPA1,
HNRNPA2B1,
HNRNPAB,
HNRNPD
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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{{author.size}} |
目前还没有研究热点人员