| Type | Description |
|---|---|
| Definition | coiled-coil domain containing 88A |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:19:00 | Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma. | 32467989 |
| 2021-02-27 13:49:00 | Quantitative acetylome and phosphorylome analysis reveals Girdin affects pancreatic cancer progression through regulating Cortactin. | 32369440 |
| 2021-01-16 15:57:00 | The Galpha-interacting vesicle-associated protein interacts with and promotes cell surface localization of GRP78 during endoplasmic reticulum stress. | 31736058 |
| 2020-03-28 11:54:00 | PP2A inhibits breast cancer metastasis via dephosphorylation of Girdin. | 30935690 |
| 2020-03-28 11:16:00 | Here, we present a 2.0-A crystal structure of Galpha i in complex with the GEM motif of GIV/Girdin. Nucleotide exchange assays, molecular dynamics simulations, and hydrogen-deuterium exchange experiments demonstrate that GEM binding to the conformational switch II causes structural changes that allosterically propagate to the hydrophobic core of the Galpha i GTPase domain | 31363053 |
| Type | IDs |
|---|---|
| Synonymous | APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, PEHO, PEHOL |
| Gene |
UniProtKB-ID:
GRDN_HUMAN,
A0A2U3TZV9_HUMAN,
O14997_HUMAN
UniprotKB:
Q3V6T2,
A0A2U3TZV9,
O14997
UniParc:
UPI0000EE25B3,
UPI000189A86B,
UPI000150AEEC,
UPI000387B36E,
UPI00000703C2,
UPI00005B7220,
UPI0000402051
EMBL:
AB125644,
BX537985,
BX538154,
D64159,
AC019198,
AC092176,
BC132736,
AB201172,
AC012358,
BX648138,
BC144320
Ensembl:
ENSG00000115355
KO:
hsa:55704
|
| Nucleutide sequences |
EMBL-CDS:
BAE44387.1,
CAD98038.1,
CAD97945.1,
BAF44475.1,
AAI44321.1,
AAX82029.1,
CAI46020.1,
AAI32737.1,
AAY14932.1,
BAA21515.1
Ensembl_TRS:
ENST00000436346,
ENST00000263630,
ENST00000642200,
ENST00000643413,
ENST00000336838,
ENST00000646796,
ENST00000413716
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000494811,
ENSP00000263630,
ENSP00000338728,
ENSP00000493703,
ENSP00000410608,
ENSP00000495919,
ENSP00000404431
RefSeq:
XP_005264483.1,
XP_016859969.1,
NP_001241872.1,
NP_060554.3,
NP_001129069.1,
XP_016859970.1,
XP_011531270.1,
XP_016859966.1,
XP_016859967.1,
XP_011531269.1,
XP_016859968.1,
XP_005264475.1,
XP_016859965.1,
XP_011531268.1,
XP_005264478.1,
NP_001352409.1
|
| Others |
UniRef100:
UniRef100_O14997,
UniRef100_Q3V6T2,
UniRef100_A0A2U3TZV9
UniRef90:
UniRef90_O14997,
UniRef90_Q3V6T2
UniRef50:
UniRef50_Q3V6T2,
UniRef50_A0A3B3VEX7
UniGene:
Hs.292925
CCDS:
CCDS46288.1,
CCDS33203.1,
CCDS58710.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员