| Type | Description |
|---|---|
| Definition | cAMP-dependent protein kinase inhibitor beta |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 11:04:00 | results indicate that PKIB promotes cell proliferation and tumorigenesis by activating the PI3K/Akt pathway in non-small cell lung cancer (NSCLC), implying that this is an important underlying mechanism that affects the progression of NSCLC | 27325557 |
| 2014-10-04 10:58:00 | mutation of the pseudosubstrate domain abolished the inhibitory activity of PKIB on protein kinase A activity, but had no effect on the interaction with GPR39, cell protection and induction of SRE-dependent transcription | 24869658 |
| 2013-07-27 12:05:00 | PKIB overexpression was strongly correlated with pAkt expression and triple-negative breast cancer, suggesting that PKIB overexpression might contribute to the tumor behavior and development of breast cancers. | 23224602 |
| 2010-01-21 00:00:00 | human PKIbeta gene (clone 436F11, GenBank with accession number: AF225513) was over-expressed in normal brain tissues | 12061725 |
| 2010-01-21 00:00:00 | PKIbeta may be a novel full-length gene related to human glioma and may provide a new way to gene therapy of glioma. | 19035091 |
| Type | IDs |
|---|---|
| Synonymous | PRKACN2 |
| Gene |
UniProtKB-ID:
IPKB_HUMAN
UniprotKB:
Q9C010
UniParc:
UPI0000423C90,
UPI0000001C4E
EMBL:
AF087873,
CH471051,
AL513481,
BC093027,
Z99129,
AL512283,
AK315151,
BC036011,
AF225513
Ensembl:
ENSG00000135549
KO:
hsa:5570
|
| Nucleutide sequences |
EMBL-CDS:
AAK00638.1,
AAH36011.1,
AAH93027.1,
BAG37599.1,
EAW48171.1,
AAM10501.1
Ensembl_TRS:
ENST00000258014,
ENST00000392490,
ENST00000368452,
ENST00000615438,
ENST00000354275,
ENST00000392491,
ENST00000368448
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346227,
ENSP00000357437,
ENSP00000376281,
ENSP00000357433,
ENSP00000480824,
ENSP00000376280,
ENSP00000258014
RefSeq:
NP_001257323.1,
NP_861460.1,
XP_011534234.1,
NP_001257324.1,
NP_861459.1,
XP_011534232.1,
XP_011534238.1,
NP_001257322.1,
NP_115860.1,
XP_011534239.1,
XP_011534237.1,
XP_011534235.1,
XP_011534233.1
|
| Others |
UniRef100:
UniRef100_Q9C010
UniRef90:
UniRef90_Q9C010
UniRef50:
UniRef50_Q9C010
UniGene:
Hs.741340,
Hs.744965
CCDS:
CCDS5126.1,
CCDS59033.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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