| Type | Description |
|---|---|
| Definition | Rap associating with DIL domain |
| Date | Results | Publications |
|---|---|---|
| 2013-06-08 11:45:00 | Studies indicate that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. +++ ERROR +++ studies establish that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. | 23097489 |
| 2013-02-23 11:54:00 | It was shown that KIF14 associates with the PDZ domain of Radil and negatively regulates Rap1-mediated inside-out integrin activation by tethering Radil on microtubules. Radil is also important for breast cancer cell proliferation and metastasis. | 23209302 |
| 2010-03-29 12:01:00 | Gbetagamma subunits enter in a protein complex with activated Rap1a and its effector Radil; this complex is required downstream of receptor stimulation for the activation of integrins and the positive modulation of cell-matrix adhesiveness. | 20048162 |
| Type | IDs |
|---|---|
| Synonymous | RASIP2 |
| Gene |
UniProtKB-ID:
RADIL_HUMAN
UniprotKB:
Q96JH8
UniParc:
UPI0000E0A787,
UPI0000423EEB,
UPI0001AE706A,
UPI0001EC9667
EMBL:
BC126311,
EF560723,
CH236953,
AK000997,
AC092610,
AK001186,
BC004919,
BC117317,
AL136731,
CH471144,
AB058752,
BC143526
Ensembl:
ENSG00000157927
KO:
hsa:55698
|
| Nucleutide sequences |
EMBL-CDS:
AAH04919.2,
BAA91459.1,
AAI43527.1,
BAB47478.1,
CAB66665.2,
AAS07559.1,
BAA91543.1,
AAI17318.1,
ABQ59033.1,
EAW87301.1,
EAL23966.1,
AAI26312.1
Ensembl_TRS:
ENST00000399583
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000382492
RefSeq:
NP_060529.4
|
| Others |
UniRef100:
UniRef100_Q96JH8
UniRef90:
UniRef90_Q96JH8
UniRef50:
UniRef50_Q96JH8
UniGene:
Hs.667336
CCDS:
CCDS43544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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