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55698 RADIL

55698

RADIL

Rap associating with DIL domain

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rap associating with DIL domain

研究结论

Date Results Publications
2013-06-08 11:45:00 Studies indicate that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. +++ ERROR +++ studies establish that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. 23097489
2013-02-23 11:54:00 It was shown that KIF14 associates with the PDZ domain of Radil and negatively regulates Rap1-mediated inside-out integrin activation by tethering Radil on microtubules. Radil is also important for breast cancer cell proliferation and metastasis. 23209302
2010-03-29 12:01:00 Gbetagamma subunits enter in a protein complex with activated Rap1a and its effector Radil; this complex is required downstream of receptor stimulation for the activation of integrins and the positive modulation of cell-matrix adhesiveness. 20048162

名称对应

Type IDs
Synonymous RASIP2
Gene
UniProtKB-ID: RADIL_HUMAN
UniprotKB: Q96JH8
UniParc: UPI0000E0A787, UPI0000423EEB, UPI0001AE706A, UPI0001EC9667
EMBL: BC126311, EF560723, CH236953, AK000997, AC092610, AK001186, BC004919, BC117317, AL136731, CH471144, AB058752, BC143526
Ensembl: ENSG00000157927
KO: hsa:55698
Nucleutide sequences
EMBL-CDS: AAH04919.2, BAA91459.1, AAI43527.1, BAB47478.1, CAB66665.2, AAS07559.1, BAA91543.1, AAI17318.1, ABQ59033.1, EAW87301.1, EAL23966.1, AAI26312.1
Ensembl_TRS: ENST00000399583
Protein sequencees
Ensembl_PRO: ENSP00000382492
RefSeq: NP_060529.4
Others
UniRef100: UniRef100_Q96JH8
UniRef90: UniRef90_Q96JH8
UniRef50: UniRef50_Q96JH8
UniGene: Hs.667336
CCDS: CCDS43544.1

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