| Type | Description |
|---|---|
| Definition | FERM domain containing 4A |
| Date | Results | Publications |
|---|---|---|
| 2017-08-05 12:27:00 | FRMD4A or inhibition of cytohesins strongly upregulated secretion of endogenous tau. These results suggest that FRMD4A, a genetic risk factor for late-onset Alzheimer's disease, regulates tau secretion by activating cytohesin-Arf6 signaling. | 27044754 |
| 2017-03-25 10:44:00 | Findings suggest that FRMD4A expression correlates with the development of tongue squamous cell carcinoma. | 27666346 |
| 2016-08-27 12:19:00 | novel microcephaly, intellectual disability and dysmorphism syndrome is associated with a mutation in FRMD4A. | 25388005 |
| 2014-04-26 12:14:00 | data suggest that FRMD4A could be a relevant candidate gene for AD risk. | 22430674 |
| 2012-09-15 11:12:00 | findings suggest FRMD4A as a novel candidate therapeutic target in HNSCC based on the key role in metastatic growth we have identified | 22564525 |
| Type | IDs |
|---|---|
| Synonymous | CCAFCA, FRMD4, bA295P9.4 |
| Gene |
UniProtKB-ID:
FRM4A_HUMAN,
Q9NW91_HUMAN
UniprotKB:
Q9P2Q2,
Q9NW91
UniParc:
UPI0000072DB3,
UPI0000366665
EMBL:
AK289693,
AB037715,
AL365495,
AL157392,
BC151244,
AC069025,
AK001072
Ensembl:
ENSG00000151474
KO:
hsa:55691
|
| Nucleutide sequences |
EMBL-CDS:
AAI51245.1,
BAF82382.1,
BAA92532.1,
BAA91492.1
Ensembl_TRS:
ENST00000357447
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350032
RefSeq:
XP_006717521.1,
XP_016871882.1,
NP_001305267.1,
XP_024303842.1,
XP_005252547.1,
XP_011517841.1,
XP_005252546.1,
XP_024303838.1,
XP_005252552.1,
NP_001305265.1,
XP_024303837.1,
XP_011517845.1,
XP_006717527.1,
XP_011517843.1,
XP_006717520.1,
XP_016871884.1,
NP_060497.3,
XP_024303840.1,
XP_024303836.1,
XP_024303839.1,
NP_001305266.1,
XP_016871883.1,
XP_011517842.1,
XP_006717523.1,
XP_016871885.1,
XP_006717522.1,
XP_024303835.1
|
| Others |
UniRef100:
UniRef100_Q9P2Q2,
UniRef100_Q9NW91
UniRef90:
UniRef90_Q8BIE6,
UniRef90_A0A493TNP3
UniRef50:
UniRef50_A0A493TNP3,
UniRef50_Q8BIE6
UniGene:
Hs.330463,
Hs.656573
CCDS:
CCDS7101.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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