| Type | Description |
|---|---|
| Definition | phosphofurin acidic cluster sorting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer. | 33028635 |
| 2020-11-28 13:15:00 | The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability. | 31988453 |
| 2018-04-21 11:21:00 | Using whole exome sequencing (WES), we identified eight additional individuals with the same p.Arg203Trp missense variant in PACS1 that we demonstrated were de novo in seven individuals with available parental DNA. | 28111752 |
| 2018-03-31 12:06:00 | PCAF and ADA3 transcriptionally regulate PACS1 and PACS1 is a key regulator of BAX/BAK oligomerization and the intrinsic (mitochondrial) pathway to apoptosis. | 28060382 |
| 2018-03-17 12:09:00 | Protein adaptation and the expanding roles of the PACS1 and PACS2 proteins in tissue homeostasis and disease has been summarized. (Review) | 28476937 |
| Type | IDs |
|---|---|
| Synonymous | MRD17, SHMS |
| Gene |
UniProtKB-ID:
PACS1_HUMAN,
A0A024R5H6_HUMAN
UniprotKB:
Q6VY07,
A0A024R5H6
UniParc:
UPI0000190973,
UPI000042AB35
EMBL:
BC009936,
CH471076,
AK096644,
BC010096,
BC055288,
AK001071,
BC003173,
AB033001,
AK056361,
BC052577,
AY320283
Ensembl:
ENSG00000175115
KO:
hsa:55690
|
| Nucleutide sequences |
EMBL-CDS:
BAA86489.1,
AAH52577.1,
BAA91491.1,
AAH55288.1,
AAH09936.1,
AAH03173.1,
BAC04831.1,
AAQ67682.1,
AAH10096.1,
BAB71164.1,
EAW74502.1,
EAW74504.1
Gene_ORFName:
hCG_1818391
Ensembl_TRS:
ENST00000320580
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316454
RefSeq:
XP_011543466.1,
XP_011543464.1,
NP_060496.2
|
| Others |
UniRef100:
UniRef100_Q6VY07
UniRef90:
UniRef90_Q6VY07
UniRef50:
UniRef50_Q6VY07
UniGene:
Hs.644326
CCDS:
CCDS8129.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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