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55684 RABL6

55684

RABL6

RAB, member RAS oncogene family like 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB, member RAS oncogene family like 6

研究结论

Date Results Publications
2021-02-02 13:26:00 High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma. 32600359
2020-06-20 11:47:00 The present work identifies RABL6A as a new inhibitor of the PP2A tumor suppressor and an essential activator of AKT in PNET cells. Our findings offer what we believe is a novel strategy of PP2A reactivation for treatment of PNETs as well as other human cancers driven by RABL6A overexpression and PP2A inactivation. 30721156
2016-10-29 11:23:00 Rb knockdown reversed RBEL1 depletion-induced tumor suppressive effects. In conclusion, the present results suggest that RBEL1 modulates cell proliferation and G1S transition by inhibiting Rb in osteosarcoma 26676380
2015-08-26 17:56:00 work identifies RABL6A as a novel negative regulator of Rb1 25273089
2014-04-12 10:51:00 Breast cancer patients with high levels of C9orf86 expression showed a significant trend towards worse survival compared to patients with low C9orf86 expression. 23977139

名称对应

Type IDs
Synonymous C9orf86, PARF, RBEL1, pp8875
Gene
UniProtKB-ID: RABL6_HUMAN
UniprotKB: Q3YEC7
UniParc: UPI0000D4D26D, UPI0000E0C208, UPI0000EF88B4, UPI000046FF03, UPI0000EE55FF, UPI0000210F94
EMBL: EF156753, AK023107, AK027586, EF156752, BC035786, BC021095, BC002945, GQ169127, AL355987, AL713707, DQ099383, GQ169126, DQ141240
Ensembl: ENSG00000196642
KO: hsa:55684
Nucleutide sequences
EMBL-CDS: BAB55213.1, AAH02945.2, AAH21095.2, ACS45171.1, ACS45172.1, AAZ73768.1, AAH35786.1, ABO84837.1, BAB14408.1, AAZ13759.1, CAD28504.1, ABO84838.1
Ensembl_TRS: ENST00000371663, ENST00000357466, ENST00000371671, ENST00000311502
Protein sequencees
Ensembl_PRO: ENSP00000350056, ENSP00000360727, ENSP00000360736, ENSP00000311134
RefSeq: NP_078994.3, NP_001167460.1, NP_001167459.1
Others
UniRef100: UniRef100_Q3YEC7
UniRef90: UniRef90_Q3YEC7
UniRef50: UniRef50_Q3YEC7
UniGene: Hs.370555
CCDS: CCDS48058.1, CCDS55353.1, CCDS55352.1

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