| Type | Description |
|---|---|
| Definition | protein kinase cAMP-activated catalytic subunit gamma |
| Date | Results | Publications |
|---|---|---|
| 2015-01-03 10:38:00 | The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes. | 25061177 |
| 2010-01-21 12:36:00 | Results suggest that can negatively regulate ERalpha, at least in part, through FoxH1. | 19711044 |
| 2010-01-21 00:00:00 | Findings show that PKIB and kinase can have critical functions of aggressive phenotype of PCs through Akt phosphorylation and that they should be a promising molecular target for PC treatment. | 19483721 |
| 2010-01-21 00:00:00 | phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which mediates platelet inhibition | 12361948 |
| 2010-01-21 00:00:00 | Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation. | 15039079 |
| Type | IDs |
|---|---|
| Synonymous | BDPLT19, KAPG, PKACg |
| Gene |
UniProtKB-ID:
KAPCG_HUMAN
UniprotKB:
P22612
UniParc:
UPI000013E448
EMBL:
BC039888,
M34182,
AJ001597,
AL162730,
DQ667175
Ensembl:
ENSG00000165059
KO:
hsa:5568
|
| Nucleutide sequences |
EMBL-CDS:
AAH39888.1,
ABG25920.1,
AAC41690.1,
CAA04863.1
Ensembl_TRS:
ENST00000377276
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366488
RefSeq:
NP_002723.2
|
| Others |
UniRef100:
UniRef100_P22612
UniRef90:
UniRef90_P22612
UniRef50:
UniRef50_P22612
UniGene:
Hs.158029
CCDS:
CCDS6625.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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