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55679 LIMS2

55679

LIMS2

LIM zinc finger domain containing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition LIM zinc finger domain containing 2

研究结论

Date Results Publications
2021-03-13 13:24:00 Fluid shear stress modulates endothelial inflammation by targeting LIMS2. 32752897
2017-01-28 10:22:00 Mammalian cells have two functional PINCH proteins, PINCH1 and PINCH2. PINCH not only binds to Nck2 and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK and parvin (IPP complex). 27590440
2016-09-03 10:07:00 Data indicate compound heterozygous missense mutations that are predicted to be pathogenic in LIM and senescent cell antigen-like domains 2 protein (LIMS2). 25589244
2015-05-16 10:11:00 Results defined the functional role of copy number variations involving PINCH-2 in cancer progression based on the field cancerization effect; cell migration and invasion through autocrine and paracrine function as part of the field cancerization effect. 25346044
2011-06-25 13:21:00 PINCH-2 mRNA is overexpressed in malignant mesothelioma 20500520

名称对应

Type IDs
Synonymous LGMD2W, MDRCMTT, PINCH-2, PINCH2
Gene
UniProtKB-ID: LIMS2_HUMAN, B3KNZ3_HUMAN, A0A024RAH1_HUMAN
UniprotKB: Q7Z4I7, B3KNZ3, A0A024RAH1
UniParc: UPI000014F8C3, UPI0001A58002, UPI00001A41DA, UPI0000D466E4, UPI00001B5BF7, UPI00001B5BF3
EMBL: BX458594, AF484961, AK055363, BC065816, AF527765, AK297645, AF527766, AF527764, AF520987, AK022470, CH471103, AC010976, AC074114, AF527770
Ensembl: ENSG00000072163
KO: hsa:55679
Nucleutide sequences
EMBL-CDS: AAH65816.1, BAG60013.1, AAM77350.1, AAQ09011.1, BAB14047.1, AAM97589.1, AAQ09012.1, AAQ09013.1, AAQ09017.1, BAG51505.1, EAW95331.1, EAW95327.1
Gene_ORFName: hCG_42603
Ensembl_TRS: ENST00000409455, ENST00000410038, ENST00000545738, ENST00000355119, ENST00000409286, ENST00000409808, ENST00000409254, ENST00000324938, ENST00000410011, ENST00000409754
Protein sequencees
Ensembl_PRO: ENSP00000386907, ENSP00000347240, ENSP00000386383, ENSP00000386637, ENSP00000386570, ENSP00000326888, ENSP00000443794, ENSP00000387002, ENSP00000386252, ENSP00000386345
RefSeq: XP_011509755.1, NP_001129509.2, NP_001154875.1, XP_024308752.1, XP_005263767.1, XP_024308751.1, XP_016859958.1, NP_001154876.1, XP_024308754.1, XP_024308753.1, XP_006712690.1, NP_001243471.1, NP_060450.2, XP_006712691.1
Others
UniRef100: UniRef100_A0A024RAH1, UniRef100_Q7Z4I7, UniRef100_B3KNZ3
UniRef90: UniRef90_A0A2I3GSX4, UniRef90_Q7Z4I7
UniRef50: UniRef50_P48059-3, UniRef50_Q7Z4I7
UniGene: Hs.469881
CCDS: CCDS54394.1, CCDS54396.1, CCDS2147.1, CCDS54395.1, CCDS58725.1

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