| Type | Description |
|---|---|
| Definition | interacts with SUPT6H, CTD assembly factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-05-14 10:54:00 | common LEDGF/p75 interaction interface shared by JPO2, PogZ, MLL1, IWS1 and HIV IN | 26245978 |
| 2015-10-10 10:18:00 | Altogether, these results indicate that a complex containing LEDGF/p75, Iws1, and Spt6 participates in regulating postintegration steps of HIV latency. | 25590759 |
| 2014-04-26 10:42:00 | IWS1, an RNA processing regulator, is phosphorylated by Akt3 and Akt1 at Ser720/Thr721 in lung cancer | 24462114 |
| 2010-01-21 00:00:00 | Here we report that the human homolog of Iws1, hIws1, physically interacts with protein arginine methyltransferases PRMT5 which methylates elongation factor Spt5 and regulates its interaction with RNA polymerase II. | 17184735 |
| 2010-01-21 00:00:00 | binding of Spt6 to Ser2-P RNAPII provides a cotranscriptional mechanism to recruit Iws1, REF1/Aly, and associated mRNA processing, surveillance, and export factors to responsive genes. | 17234882 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IWS1_HUMAN
UniprotKB:
Q96ST2
UniParc:
UPI000006E1EB,
UPI0000141981,
UPI000006EA82
EMBL:
BC110537,
AL834178,
AK000868,
AK027561,
BC110536,
AK001717,
AK056881,
BC065279
Ensembl:
ENSG00000163166
KO:
hsa:55677
|
| Nucleutide sequences |
EMBL-CDS:
AAH65279.1,
AAI10537.1,
BAB71301.1,
BAA91858.1,
BAA91402.1,
BAB55198.1,
CAD38875.1,
AAI10538.1
Ensembl_TRS:
ENST00000295321
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295321
RefSeq:
XP_006712689.1,
XP_011509752.1,
XP_016859957.1,
XP_005263764.1,
XP_016859956.1,
NP_060439.2
|
| Others |
UniRef100:
UniRef100_Q96ST2
UniRef90:
UniRef90_Q96ST2
UniRef50:
UniRef50_Q96ST2
UniGene:
Hs.469879
CCDS:
CCDS2146.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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