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55665 URGCP

55665

URGCP

upregulator of cell proliferation

protein-coding

Homo sapiens

基因描述

Type Description
Definition upregulator of cell proliferation

研究结论

Date Results Publications
2021-02-27 13:49:00 LINC00514 drives osteosarcoma progression through sponging microRNA-708 and consequently increases URGCP expression. 32325430
2019-12-14 12:15:00 URG4 overexpression in breast ductal carcinomas is significantly associated with good prognostic parameters. 30680688
2019-07-06 11:21:00 All these results suggested that URGCP accelerates glioma growth through the NF-kappaB/c-myc/miR-16/Cyclin D1/E1 pathway, and both URGCP and miR-16 function as a novel cell cycle regulators in glioma and could be considered as potential targets for glioma therapy. 29044221
2018-06-16 10:39:00 Relationship between URG4/URGCP expression and clinicopathologic characteristics were evaluated and significant results were in various cancer types (review). 29775749
2017-04-29 11:00:00 miR-519 inhibited URG4 expression by directly binding to the 3'UTR of URG4. miR-519 inhibited Cyclin D1 expression and the phosphorylation level of Rb, and increased p21 and p27 expression, confirming miR-519 blocked G1/S transition. 28315691

名称对应

Type IDs
Synonymous URG4
Gene
UniProtKB-ID: URGCP_HUMAN, B7Z7T1_HUMAN, B2RAT5_HUMAN, A0A024RA74_HUMAN
UniprotKB: Q8TCY9, B7Z7T1, B2RAT5, A0A024RA74
UniParc: UPI000020EE99, UPI00005A77C8, UPI0000E0AA41, UPI0001915215, UPI000020EE94, UPI000020EE9D
EMBL: AK000661, AB040940, AL833744, AY078404, AK314339, CR749398, BC018426, BX640797, CH471073, AK302459, AC004985
Ensembl: ENSG00000106608
KO: hsa:55665
Nucleutide sequences
EMBL-CDS: CAE45880.1, CAH18244.1, AAH18426.2, BAA91312.1, CAH56246.1, AAL83710.1, BAA96031.1, BAH13717.1, BAG36982.1, EAW94174.1, EAW94176.1
Gene_ORFName: hCG_19423
Ensembl_TRS: ENST00000402306, ENST00000336086, ENST00000453200, ENST00000443736
Protein sequencees
Ensembl_PRO: ENSP00000392136, ENSP00000336872, ENSP00000384955, ENSP00000396918
RefSeq: NP_001071132.1, NP_001277004.1, NP_060390.3, NP_001071131.1, NP_001277005.1
Others
UniRef100: UniRef100_A0A024RA74, UniRef100_B2RAT5, UniRef100_Q8TCY9, UniRef100_B7Z7T1
UniRef90: UniRef90_Q8TCY9
UniRef50: UniRef50_Q8TCY9
UniGene: Hs.663312
CCDS: CCDS47578.1, CCDS47577.1, CCDS43572.1

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