| Type | Description |
|---|---|
| Definition | DEAD-box helicase 27 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 13:01:00 | Data found that DDX27 expression is significantly up-regulated in colorectal cancer (CRC) at mRNA and protein levels. DDX27 mRNA overexpression was positively correlated with DNA copy number gain and associated with poor prognosis in CRC patients. Further evidences prove that DDX27 plays a pivotal oncogenic role in CRC. | 29535419 |
| 2015-08-15 10:35:00 | The DDX27 can interact specifically with the Pes1 and Bop1 but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex. | 25825154 |
| 2015-06-20 12:50:00 | Levels of DDX27 mRNA and protein were increased in early-stage gastric tumors, and may be a potential diagnostic and prognostic marker for Gastric cancer. | 25742747 |
| Type | IDs |
|---|---|
| Synonymous | DRS1, Drs1p, HSPC259, PP3241, RHLP, dJ686N3.1 |
| Gene |
UniProtKB-ID:
DDX27_HUMAN,
B7Z6D5_HUMAN
UniprotKB:
Q96GQ7,
B7Z6D5
UniParc:
UPI000006F211,
UPI0000140DCA
EMBL:
AF336851,
BC130275,
AL357560,
BC144125,
BC009304,
AL049766,
AK022979,
AK000603,
BC126287,
AK300135,
AF193054,
BC016060,
AY044431,
AF161377,
BC011927
Ensembl:
ENSG00000124228
KO:
hsa:55661
|
| Nucleutide sequences |
EMBL-CDS:
AAH11927.2,
AAI44126.1,
AAG22482.1,
AAK21271.1,
AAI30276.1,
AAI26288.1,
AAK95821.1,
AAH09304.2,
AAH16060.2,
BAA91284.1,
AAF28937.1,
BAB14343.1,
BAH13221.1
Gene_ORFName:
PP3241,
HSPC259
Ensembl_TRS:
ENST00000622530,
ENST00000371764,
ENST00000618172
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360828,
ENSP00000483495,
ENSP00000482680
RefSeq:
NP_001335116.2,
NP_060365.8
|
| Others |
UniRef100:
UniRef100_Q96GQ7
UniRef90:
UniRef90_Q96GQ7
UniRef50:
UniRef50_Q96GQ7
UniGene:
Hs.65234
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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