| Type | Description |
|---|---|
| Definition | transmembrane protein 127 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:43:00 | The TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules. | 32526160 |
| 2021-02-27 13:54:00 | Functional Characterization of TMEM127 Variants Reveals Novel Insights into Its Membrane Topology and Trafficking. | 32575117 |
| 2019-09-28 10:54:00 | n the present cases, the clinical picture does not seem to be very different from heterozygous TMEM127 mutation carriers, except for a relatively large tumor size and more pronounced plasma metanephrine concentration. It is unclear whether the mental retardation is causally related to homozygosity of the TMEM127 mutations. | 29282712 |
| 2019-02-16 11:15:00 | We found that under nutrient-rich conditions TMEM127 expression reduces mTORC1 recruitment to Rags. In addition, TMEM127 interacts with LAMTOR in an amino acid-dependent manner and decreases the LAMTOR1-vATPase association, while TMEM127-vATPase binding requires intact lysosomal acidification but is amino acid independent | 29547888 |
| 2017-09-30 11:59:00 | The SDHA, TMEM127, MAX, and SDHAF2 genes contribute to hereditary pheochromocytoma and paraganglioma. | 28384794 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TM127_HUMAN,
Q9H6I0_HUMAN,
C9J4H2_HUMAN
UniprotKB:
O75204,
Q9H6I0,
C9J4H2
UniParc:
UPI0000207C61,
UPI0000071BC7,
UPI000000D96F
EMBL:
BC028575,
AK025910,
AC004020,
BC039892,
AC012307,
AC021188,
CH471207,
AK000514
Ensembl:
ENSG00000135956
KO:
hsa:55654
|
| Nucleutide sequences |
EMBL-CDS:
AAC23494.1,
EAW71379.1,
EAW71376.1,
AAY24224.1,
EAW71377.1,
BAA91220.1,
AAH39892.1,
EAW71378.1,
AAH28575.1,
BAB15279.1
Ensembl_TRS:
ENST00000432959,
ENST00000258439,
ENST00000435268
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000416660,
ENSP00000258439,
ENSP00000411810
RefSeq:
NP_001180233.1,
XP_016859939.1,
XP_016859941.1,
NP_060319.1
|
| Others |
UniRef100:
UniRef100_Q9H6I0,
UniRef100_O75204
UniRef90:
UniRef90_O75204,
UniRef90_Q9H6I0
UniRef50:
UniRef50_O75204,
UniRef50_Q9H6I0
UniGene:
Hs.164303,
Hs.735706
CCDS:
CCDS2018.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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