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5563 PRKAA2

5563

PRKAA2

protein kinase AMP-activated catalytic subunit alpha 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase AMP-activated catalytic subunit alpha 2

研究结论

Date Results Publications
2020-12-19 13:44:00 RSK2 protects human breast cancer cells under endoplasmic reticulum stress through activating AMPKalpha2-mediated autophagy. 32958832
2019-10-26 10:48:00 activation increased the expression and nuclear localization of Twist1 which regulated epithelial-mesenchymal transition. 29950484
2019-10-19 11:35:00 Mechanistically, AMP-activated protein kinase (AMPK)-mediated phosphorylation of BECN1 at Ser90/93/96 is required for BECN1-SLC7A11 complex formation and lipid peroxidation. 30057310
2019-05-25 10:42:00 A double-negative feedback loop between Akt and AMPK controls the switch between matrix-attached and matrix-detached states needed to coordinate cell growth and survival during breast cancer metastasis. 29339542
2018-10-20 10:38:00 It is an intracellular central metabolic sensor as well as a regulator, has been demonstrated to play significant roles in the contracting skeletal muscles, suggesting that AMPK should be one of the key molecules mediating metabolic effects during physical exercise. 30270274

名称对应

Type IDs
Synonymous AMPK, AMPK2, AMPKa2, PRKAA
Gene
UniProtKB-ID: AAPK2_HUMAN
UniprotKB: P54646
UniParc: UPI00001250A9
EMBL: U06454, BC069740, BC069823, AL035705, BC069680
Ensembl: ENSG00000162409
KO: hsa:5563
Nucleutide sequences
EMBL-CDS: AAA64745.1, AAH69740.1, AAH69823.1, AAH69680.1
Ensembl_TRS: ENST00000371244
Protein sequencees
Ensembl_PRO: ENSP00000360290
RefSeq: XP_016857183.1, XP_016857182.1, XP_016857181.1, NP_006243.2
Others
UniRef100: UniRef100_P54646
UniRef90: UniRef90_P54646
UniRef50: UniRef50_P54646
UniGene: Hs.437039
CCDS: CCDS605.1

全选

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研究热度

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