| Type | Description |
|---|---|
| Definition | autophagy and beclin 1 regulator 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:01:00 | The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes. | 32616651 |
| 2020-09-19 16:28:00 | Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin. | 29101240 |
| 2019-10-05 11:04:00 | CRL4(AMBRA)(1) modulates signaling and HIV-1 infectivity that are regulated by CRL5(SOCS)(3) and CRL5(VIF), respectively. Thus, by discovering a substrate of CRL4(AMBRA)(1), ELOC, the shared adapter of CRL5 ubiquitin ligases, we uncovered a novel CRL cross-regulation pathway. | 30166453 |
| 2019-03-23 11:01:00 | AMBRA1 is a key modulator of T cell differentiation. Through its ability to interact with the phosphatase PP2A, AMBRA1 promotes the FOXO3 stability. | 30513302 |
| 2019-01-19 10:26:00 | AMBRA1 regulates mitophagy through a novel pathway, in which HUWE1 and IKKalpha are key factors, shedding new lights on the regulation of mitochondrial quality control and homoeostasis in mammalian cells. | 30217973 |
| Type | IDs |
|---|---|
| Synonymous | DCAF3, WDR94 |
| Gene |
UniProtKB-ID:
AMRA1_HUMAN,
A0A075B6T1_HUMAN
UniprotKB:
Q9C0C7,
A0A075B6T1
UniParc:
UPI0000EE3937,
UPI0000EE394F,
UPI00015789B2,
UPI0000237851,
UPI00005A6107,
UPI00033362A5,
UPI0001627788
EMBL:
KC877408,
AC115097,
AL834190,
AC116021,
KF455381,
AK000301,
BC045609,
CH471064,
AC127035,
AK023197,
DQ870924,
AC024293,
AB051523
Ensembl:
ENSG00000110497
KO:
hsa:55626
|
| Nucleutide sequences |
EMBL-CDS:
BAB21827.1,
ABI74670.1,
EAW68001.1,
EAW67996.1,
EAW67999.1,
AAH45609.1,
BAB14457.1,
BAA91067.1
Ensembl_TRS:
ENST00000528950,
ENST00000534300,
ENST00000314845,
ENST00000458649,
ENST00000533727
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415327,
ENSP00000431926,
ENSP00000318313,
ENSP00000433945,
ENSP00000433372
RefSeq:
NP_060219.2,
XP_006718322.1,
NP_001354397.1,
NP_001254711.1,
NP_001354398.1,
NP_001287660.1,
NP_001354400.1,
XP_005253068.1,
XP_024304374.1,
NP_001254712.1,
NP_001354399.1,
NP_001373940.1,
XP_024304373.1
|
| Others |
UniRef100:
UniRef100_Q9C0C7,
UniRef100_A0A075B6T1
UniRef90:
UniRef90_Q9C0C7
UniRef50:
UniRef50_Q9C0C7
UniGene:
Hs.654644
CCDS:
CCDS31475.1,
CCDS73281.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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