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55619 DOCK10

55619

DOCK10

dedicator of cytokinesis 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition dedicator of cytokinesis 10

研究结论

Date Results Publications
2021-02-06 13:52:00 Expression of DOCK10.1 protein revealed with a specific antiserum: insights into regulation of first exon isoforms of DOCK10. 32112301
2019-05-04 11:41:00 we identified the transcription factor FoxO1 as a potential mediator of ERK2-induced EMT, and thus we investigated the mechanism by which ERK2 regulates FoxO1. Additionally, our analysis revealed that ERK2 induced the expression of Dock10, a Rac1/Cdc42 GEF, during EMT 30728292
2011-10-22 10:11:00 T cells and B cells exhibited inverse expression patterns of the DOCK10 isoforms 21514340
2010-01-21 00:00:00 Dock10 could represent a point of convergence for interleukin 4 signalling and small Rho GTPase function in B cells. 18499258
2010-01-21 00:00:00 Silencing DOCK10 expression in melanoma promotes conversion to mesenchymal migration and is associated with decreased MLC2 phosphorylation and increased Rac1 activation. 18835169

名称对应

Type IDs
Synonymous DRIP2, Nbla10300, ZIZ3
Gene
UniProtKB-ID: DOC10_HUMAN
UniprotKB: Q96BY6
UniParc: UPI000188191A, UPI00020530A7, UPI000021D2A7
EMBL: AK001253, AC017095, AK000227, BC015018, AC011739, CR749492, AB014594, AC093806, EU236710
Ensembl: ENSG00000135905
KO: hsa:55619
Nucleutide sequences
EMBL-CDS: BAA91583.1, AAH15018.1, BAA91022.1, BAA31669.2, CAH18316.1, ABY70713.2
Ensembl_TRS: ENST00000258390, ENST00000409592
Protein sequencees
Ensembl_PRO: ENSP00000386694, ENSP00000258390
RefSeq: XP_016859934.1, XP_006712680.1, NP_055504.2, XP_016859930.1, XP_016859932.1, XP_016859936.1, XP_016859935.1, XP_016859931.1, XP_016859933.1, NP_001277192.1, NP_001350691.1
Others
UniRef100: UniRef100_Q96BY6
UniRef90: UniRef90_Q96BY6
UniRef50: UniRef50_Q8BZN6
UniGene: Hs.46578
CCDS: CCDS74661.1, CCDS46528.1

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