Type | Description |
---|---|
Definition | taspase 1 |
Date | Results | Publications |
---|---|---|
2019-10-26 10:22:00 | TASP1 is a novel disease-related gene that is associated with a disease phenotype overlapping with Wiedemann-Steiner syndrome as both are caused by defects in the same pathway. | 29633245 |
2019-09-14 10:32:00 | Taspase 1 processing promotes TFIIA's nuclear accumulation by evolutionary conserved nuclear export signal (NES, amino acids 21VINDVRDIFL30) masking, and modulates its transcriptional activity. | 28992066 |
2019-07-20 11:52:00 | Proteolytic processing of TFIIA by Taspase1 was found to mask evolutionary conserved nuclear export signal, thereby promoting nuclear localization and transcriptional activation of TFIIA target genes, such as CDKN2A. | 29097782 |
2017-09-16 10:47:00 | Studies indicate that threonine Aspartase1 (Taspase1) is overexpressed in numerous liquid and solid malignancies and was characterized as a 'non-oncogene addiction' protease. | 26657154 |
2016-08-13 10:07:00 | simultaneous expression of the leukemogenic AF4-MLL and dnTASP1 causes the disappearance of the leukemogenic oncoprotein, because the uncleaved AF4-MLL protein (328 kDa) is subject to proteasomal degradation. | 26137584 |
Type | IDs |
---|---|
Synonymous | C20orf13, dJ585I14.2 |
Gene |
UniProtKB-ID:
TASP1_HUMAN
UniprotKB:
Q9H6P5
UniParc:
UPI0001915370,
UPI00000382E5,
UPI0001914DE0
EMBL:
AK304488,
BC025266,
AL121782,
AL133463,
AK025671,
AK299940,
AL121754,
AK316311,
AK000219,
AL050320,
AL158089
Ensembl:
ENSG00000089123
KO:
hsa:55617
|
Nucleutide sequences |
EMBL-CDS:
BAH14682.1,
BAA91018.1,
AAH25266.1,
BAH13176.1,
BAB15209.1,
BAH14199.1
Ensembl_TRS:
ENST00000337743
|
Protein sequencees |
Ensembl_PRO:
ENSP00000338624
RefSeq:
XP_011527594.1,
NP_001310532.1,
XP_016883419.1,
XP_016883416.1,
XP_016883417.1,
NP_060184.2,
NP_001310531.1,
XP_016883420.1,
XP_016883418.1,
XP_011527596.1,
NP_001310533.1
|
Others |
UniRef100:
UniRef100_Q9H6P5
UniRef90:
UniRef90_Q9H6P5
UniRef50:
UniRef50_Q9H6P5
UniGene:
Hs.348297
CCDS:
CCDS13116.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员