| Type | Description |
|---|---|
| Definition | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:21:00 | ACAP4 physically interacts with CrkII. Functional characterization showed that the interaction is required for the recruitment of ACAP4 to the plasma membrane where ACAP4 functions to regulate the recycling of the signal transducer integrin beta1. | 31182282 |
| 2019-09-21 11:27:00 | ARF6 GTPase-activating protein ACAP4 regulates CCL18-elicited breast cancer cell migration via the acetyltransferase PCAF-mediated acetylation. CCL18 stimulation elicited breast cancer cell migration and invasion via PCAF-dependent acetylation. | 30395269 |
| 2019-02-16 11:20:00 | MiR-143-3p acts as an anti-oncogene by downregulating ITGA6/ASAP3 protein expression and could offer new insight into potential therapeutic targets for CRC. | 30536996 |
| 2017-09-30 12:12:00 | Results show that ASAP3 was amplified in colorectal cancer (CRC) tissues, and its upregulation was associated with poor prognosis of patients with CRC. Also, it promoted growth of colon tumors, and accelerated cell invasion and migration through its binding to NEMO. These results suggest that ASAP3 acts as an oncogene. | 28502111 |
| 2014-08-30 10:41:00 | The data, for the first time, link ASAP3 with ACTG1 in the regulation of cytoskeletal maintenance and cell motility | 24284654 |
| Type | IDs |
|---|---|
| Synonymous | ACAP4, CENTB6, DDEFL1, UPLC1 |
| Gene |
UniProtKB-ID:
ASAP3_HUMAN,
A0A024RAB1_HUMAN,
B4DRP2_HUMAN
UniprotKB:
Q8TDY4,
A0A024RAB1,
B4DRP2
UniParc:
UPI00017A6F2D,
UPI00017A7A2B,
UPI00001A5EE2,
UPI0000071371
EMBL:
BC052305,
AB056749,
AK000206,
AK092291,
AK295100,
AL357134,
AL021154,
BC060786,
AK299359,
CH471134
Ensembl:
ENSG00000088280,
ENSG00000282854
KO:
hsa:55616
|
| Nucleutide sequences |
EMBL-CDS:
AAH52305.1,
BAA91008.1,
BAG58136.1,
BAG52522.1,
BAB85677.1,
EAW95050.1,
AAH60786.1,
EAW95051.1,
EAW95053.1,
BAG61354.1
Gene_ORFName:
hCG_1812045
Ensembl_TRS:
ENST00000336689,
ENST00000495646,
ENST00000437606,
ENST00000634561,
ENST00000634513,
ENST00000635198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000338769,
ENSP00000488946,
ENSP00000408826,
ENSP00000488934,
ENSP00000488953,
ENSP00000436150
RefSeq:
XP_016857176.1,
XP_016857177.1,
NP_060177.2,
NP_001137250.1,
XP_016857174.1,
XP_011540057.1,
XP_016857178.1,
XP_016857175.1
|
| Others |
UniRef100:
UniRef100_B4DRP2,
UniRef100_Q8TDY4
UniRef90:
UniRef90_Q8TDY4
UniRef50:
UniRef50_Q8TDY4
UniGene:
Hs.437379
CCDS:
CCDS235.1,
CCDS44087.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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