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55602 CDKN2AIP

55602

CDKN2AIP

CDKN2A interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition CDKN2A interacting protein

研究结论

Date Results Publications
2018-05-19 11:46:00 a comprehensive current understanding into the molecular mechanisms of CARF functions in regulation of DNA damage response, cell cycle checkpoints, cell survival and death signaling pathways. 28754531
2018-05-05 11:52:00 report that CARF (Collaborator of ARF) is a new target of miR-335 that regulates its growth suppressor function by complex crosstalk with other proteins including p16(INK4A), pRB, HDM2 and p21(WAF1) 27457128
2018-02-24 10:35:00 Oncogenic functions of CARF in hepatocellular carcinoma tumorigenesis is a result of activation of beta-catenin/TCF signaling. 27829235
2016-08-13 11:14:00 CARF promotes carcinogenesis in p53-deficient cells by repressing p21WAF1 and promoting cell cycle progression. 26278998
2016-04-30 11:14:00 The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus. 26531822

名称对应

Type IDs
Synonymous CARF
Gene
UniProtKB-ID: CARF_HUMAN, B3KTW3_HUMAN, J3KNE1_HUMAN
UniprotKB: Q9NXV6, B3KTW3, J3KNE1
UniParc: UPI000178E005, UPI000004A077, UPI0001D3B9F8
EMBL: AK096180, CH471056, AF246705, BC022270, AC112698, AK000043
Ensembl: ENSG00000168564
KO: hsa:55602
Nucleutide sequences
EMBL-CDS: EAX04691.1, AAF68967.1, AAH22270.1, BAA90902.1, BAG53225.1
Ensembl_TRS: ENST00000504169, ENST00000302350
Protein sequencees
Ensembl_PRO: ENSP00000427108, ENSP00000303788
RefSeq: NP_060102.1, NP_001304272.1
Others
UniRef100: UniRef100_Q9NXV6, UniRef100_J3KNE1
UniRef90: UniRef90_Q9NXV6, UniRef90_J3KNE1
UniRef50: UniRef50_Q5U2X0-2, UniRef50_Q9NXV6
UniGene: Hs.644077
CCDS: CCDS34110.1

全选

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研究热度

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