| Type | Description |
|---|---|
| Definition | RNA binding region (RNP1, RRM) containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-07 10:51:00 | The authores propose that both the C-RRM folding defect and nonsense-mediated decay (NMD)-mediated decrease in the levels of the U11/U12-65K protein reduce formation of the U12-type intron recognition complex and missplicing of a subset of minor introns leading to pituitary hypoplasia and a subsequent defect in growth hormone secretion. | 29255062 |
| 2018-06-02 11:10:00 | Study shows that the C-terminal RNA recognition motif of p65 binds to the distal 3' stem-loop of U6atac. By using a binary splice site mutation suppressor assay, results demonstrate that p65 protein-binding apical stem-loop of U12 snRNA can be replaced by this U6atac distal 3' stem-loop. | 27510544 |
| 2014-11-08 10:16:00 | Exome analysis of one proband revealed missense (c.1320C>A, p.P474T) and nonsense (c.1504C>T, p.R502X) mutations in the RNPC3 gene. | 24480542 |
| 2010-01-21 00:00:00 | U11/U12-65K contribute to di-snRNP formation and intron bridging in the minor prespliceosome | 16096647 |
| Type | IDs |
|---|---|
| Synonymous | IGHD5, RBM40, RNP, SNRNP65 |
| Gene |
UniProtKB-ID:
RNPC3_HUMAN
UniprotKB:
Q96LT9
UniParc:
UPI000006E703,
UPI00015DA56A
EMBL:
CH471097,
AL137730,
BC010697,
AK057799,
AK289844,
BX322653,
AY099329,
AC105272,
AB058742,
BK005195,
AC095032,
AK000015
Ensembl:
ENSG00000185946
KO:
hsa:55599
|
| Nucleutide sequences |
EMBL-CDS:
EAW72905.1,
BAB47468.1,
AAH10697.2,
BAA90885.1,
EAW72906.1,
CAB70897.2,
EAW72901.1,
BAF82533.1,
AAM45139.1,
BAB71580.1,
DAA05493.1
Ensembl_TRS:
ENST00000524631,
ENST00000533099,
ENST00000423855
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000391432,
ENSP00000432886,
ENSP00000437278
RefSeq:
NP_060089.1
|
| Others |
UniRef100:
UniRef100_Q96LT9
UniRef90:
UniRef90_Q96LT9
UniRef50:
UniRef50_Q96LT9
UniGene:
Hs.632423
CCDS:
CCDS781.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33060197 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo GarcÃa-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan |
2020-12-04 | - |
| 31076518 |
Mol Cell Proteomics Manal Alsulami , Nayla Munawar , Eugene Dillon , Giorgio Oliviero , Kieran Wynne , Mona Alsolami , Catherine Moss , Peadar à Gaora , Fergal O'Meara , David Cotter , Gerard Cagney |
2019-07-01 | - |
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 29802200 |
J Biol Chem Isaac Bishof , Eric B Dammer , Duc M Duong , Sean R Kundinger , Marla Gearing , James J Lah , Allan I Levey , Nicholas T Seyfried |
2018-07-13 | - |
| 29509190 |
Sci Data Giorgio Giurato , Giovanni Nassa , Annamaria Salvati , Elena Alexandrova , Francesca Rizzo , Tuula A Nyman , Alessandro Weisz , Roberta Tarallo |
2018-03-06 | - |
| 29255062 |
RNA Antto J Norppa , Tuuli M Kauppala , Harri A Heikkinen , Bhupendra Verma , Hideo Iwaï , Mikko J Frilander |
2018-03-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27510544 |
Sci Rep Jagjit Singh , Kavleen Sikand , Heike Conrad , Cindy L Will , Anton A Komar , Girish C Shukla |
2016-08-11 | - |
| 26354767 |
Genetics Melanie L Bailey , Tejomayee Singh , Patricia Mero , Jason Moffat , Philip Hieter |
2015-11-01 |
LINC00173,
TUBA1B,
CDR2,
DLC1,
SPAG11B,
UBAC1,
SLC35A1,
COPS6,
DIDO1,
EFHC1,
TBCB,
MTFMT,
ZC3H18,
COL1A2,
COL12A1,
DNAJC21,
LETM2,
RALYL,
ZNF563,
B3GALNT2,
CYBB,
CYLD,
TMEM65,
AP2A1,
SPRED1,
MMAA,
EPOR,
FANCD2,
C6orf136,
RSBN1L,
FGA,
PUF60,
TXLNGY,
EBF3,
GAK,
TRIM58,
NECTIN3,
FAM32A,
RBMX,
GMDS,
OR51V1,
CDH19,
C5orf51,
C5orf64,
GRIK3,
GRM3,
CPSF1,
EIF4E3,
LRRTM1,
LCE1B,
ITGAV,
GAMTP1,
HERC2P2,
LPA,
MEP1A,
MOCS1,
NUDT4P1,
PALM2-AKAP2,
NDUFB9,
RERE,
TRAT1,
PHF20L1,
CDK18,
NAT8B,
CINP,
ZFR,
RAB4B,
POLR2K,
EXOSC4,
SPDL1,
SRBD1,
RFWD3,
FBXW7,
TNFRSF19,
H2AFY2,
RNPC3,
TMEM126B,
C8orf44,
PRPSAP1,
C5orf15,
PTGDS,
SENP7,
SHROOM4,
PTPRN2,
RAG1,
VPS16,
SLC17A1,
SNRNP70,
SNRPB2,
SNRPF,
SPTBN1,
SSBP1,
SUPT6H,
MED22,
BUB1B,
OSGIN2,
MPPED1,
GGCT,
NELFE
|
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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