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55593 OTUD5

55593

OTUD5

OTU deubiquitinase 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition OTU deubiquitinase 5

研究结论

Date Results Publications
2020-09-19 16:28:00 OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity. 32826889
2019-10-19 10:58:00 OTUD5 is a specific deubiquitinase for Ku80 and is an important and positive regulator of non-homologous end joining repair. 30980112
2019-08-24 11:23:00 OTUD5 localizes to DNA double strand breaks, interacts with UBR5 and represses the RNA Pol II elongation and RNA synthesis. 30508113
2015-04-25 12:51:00 Findings have uncovered an apoptotic signaling cascade linking PDCD5, OTUD5, and p53 during genotoxic stress responses. 25499082
2014-06-21 10:17:00 OTUD5 is required for the stabilization and the activation of a p53 response 24143256

名称对应

Type IDs
Synonymous DUBA
Gene
UniProtKB-ID: OTUD5_HUMAN, A0A024QZ09_HUMAN
UniprotKB: Q96G74, A0A024QZ09
UniParc: UPI000006ED2A, UPI000054E4AC, UPI0000211FE2, UPI00017A6FCC, UPI000006FB1D
EMBL: AK026260, BC028225, AF207550, AK294590, AK022612, BC098440, AL137509, BC009917, CH471224
Ensembl: ENSG00000068308
KO: hsa:55593
Nucleutide sequences
EMBL-CDS: EAW50724.1, AAH98440.1, AAH09917.1, CAB70778.1, BAG57778.1, BAB15416.1, AAH28225.1, BAB14131.1, EAW50726.1, EAW50725.1
Gene_ORFName: hCG_19842
Ensembl_TRS: ENST00000428668, ENST00000376488, ENST00000396743, ENST00000156084
Protein sequencees
Ensembl_PRO: ENSP00000156084, ENSP00000401629, ENSP00000365671, ENSP00000379969
RefSeq: NP_001129629.1, XP_006724600.1, XP_024308165.1, XP_005278096.1, NP_060072.1, NP_001129630.1, XP_016885117.1, XP_011542234.1, XP_005272679.1, XP_011542236.1, XP_016885118.1, NP_001129631.1, XP_016885119.1, XP_024308164.1, XP_005278099.1
Others
UniRef100: UniRef100_Q96G74
UniRef90: UniRef90_Q96G74
UniRef50: UniRef50_Q96G74
UniGene: Hs.496098
CCDS: CCDS48104.1, CCDS14313.1, CCDS48105.1

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