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55576 STAB2

55576

STAB2

stabilin 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition stabilin 2

研究结论

Date Results Publications
2021-03-20 13:30:00 Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease. 32457982
2020-08-01 13:57:00 Macrophages likely require full-length Stab2 for efficient binding and phagocytosis of bacteria or apoptotic cells, since cell-binding domains are throughout the receptor. 31500161
2019-09-28 11:23:00 stabilin-2-expressing cells bind and internalize VWF and FVIII in a VWF-dependent manner, and the stabilin-2 variant p.E2377K significantly decreased stabilin-2 expression and impaired VWF endocytosis in a heterologous expression system 30124466
2018-05-12 11:03:00 Structural Determinants for the Interactions of Chemically Modified with the Stabilin-2 Clearance Receptor. 29589907
2017-04-08 10:31:00 Data show that the hyaluronan receptor for endocytosis (HARE) NPLY2519 motif is necessary for both extracellular signal-regulated kinases ERK1/2 and NF-kappa B (NF-kappaB)signaling and that Tyr2519 is critical for these functions. 27100626

名称对应

Type IDs
Synonymous FEEL2, FELE-2, FELL2, FEX2, HARE, SCARH1
Gene
UniProtKB-ID: STAB2_HUMAN
UniprotKB: Q8WWQ8
UniParc: UPI00001ADDF4
EMBL: AK074051, AY227444, AJ295695, AY311388, AF160476, AK160380, AK024503, AB052958
Ensembl: ENSG00000136011
KO: hsa:55576
Nucleutide sequences
EMBL-CDS: BAC15608.1, AAO39681.1, AAP74958.1, AAF82398.1, BAD18723.1, BAB84877.1, BAB15793.1, CAC82105.1
Ensembl_TRS: ENST00000388887
Protein sequencees
Ensembl_PRO: ENSP00000373539
RefSeq: XP_011536844.1, XP_011536839.1, XP_011536841.1, XP_011536843.1, XP_016875074.1, XP_011536840.1, NP_060034.9
Others
UniRef100: UniRef100_Q8WWQ8
UniRef90: UniRef90_Q8WWQ8
UniRef50: UniRef50_Q8WWQ8
UniGene: Hs.408249
CCDS: CCDS31888.1

全选

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