| Type | Description |
|---|---|
| Definition | collagen and calcium binding EGF domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-07-25 11:06:00 | Collagen domains of CCBE1 are crucial for the activation of VEGFC in vitro and in vivo. The EGF domains of CCBE1 are dispensable for regulation of VEGFC processing in vitro, however, they are necessary for full lymphangiogenic activity of CCBE1 in vivo. | 25814692 |
| 2014-05-03 11:20:00 | In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1, and Vegfc-driven sprouting is enhanced by local Ccbe1 overexpression. Moreover, Vegfc- and Vegfr3-dependent Erk signaling is impaired in the absence of Ccbe1. | 24523457 |
| Type | IDs |
|---|---|
| Synonymous | fof |
| Gene |
UniProtKB-ID:
CCBE1_DANRE
UniprotKB:
A8WGB1
UniParc:
UPI00017604B2
EMBL:
BC154643
Ensembl:
ENSDARG00000086158
KO:
dre:555629
|
| Nucleutide sequences |
EMBL-CDS:
AAI54644.1
Ensembl_TRS:
ENSDART00000127963
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000106577
RefSeq:
XP_021324522.1,
NP_001157395.1,
XP_017208271.1
|
| Others |
UniRef100:
UniRef100_A8WGB1
UniRef90:
UniRef90_A8WGB1
UniRef50:
UniRef50_Q6UXH8
UniGene:
Dr.110996
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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