PLXNA3 - plexin A3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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55558 PLXNA3

基因描述

Type	Description
Definition	plexin A3

研究结论

Date	Results	Publications
2018-08-11 12:02:00	Exome analysis of Kuwaiti multiple sclerosis patients revealed a missense variant (rs5945430) in Plexin A3 (PLXNA3) gene (Xq28) associated with male-specific MS severity and disability.	28536997
2016-04-02 11:34:00	Data indicate that plexin A1-4 (PLXNA1-4) mediation of neuroanatomical traits can be detected using in vivo neuroimaging techniques.	25518740
2011-12-17 11:40:00	in vitro analysis on PLXNA3 also suggest that this gene may have some form of growth suppressive role in breast cancer, in addition to a similar role for the gene previously reported in ovarian cancer.	21925246
2010-01-21 00:00:00	Data show that the expression of Sema3A receptors (neuropilin-1 (NRP-1), NRP-2, plexin A1, plexin A2, and plexin A3) significantly increased during M-CSF-mediated differentiation of monocytes into macrophages.	19480842

名称对应

Type	IDs
Synonymous	6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6
Gene	UniProtKB-ID: PLXA3_HUMAN UniprotKB: P51805 UniParc: UPI000004E900 EMBL: BX936365, X87852 Ensembl: ENSG00000130827 KO: hsa:55558
Nucleutide sequences	EMBL-CDS: CAA61132.1 Ensembl_TRS: ENST00000369682
Protein sequencees	Ensembl_PRO: ENSP00000358696 RefSeq: XP_005274762.2, NP_059984.3, XP_011529485.1, XP_006724892.1, XP_005274763.2
Others	UniRef100: UniRef100_P51805 UniRef90: UniRef90_P51805 UniRef50: UniRef50_P70208 UniGene: Hs.632839 CCDS: CCDS14752.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31391242	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. J Cell Sci Marcel Nowak , Benjamin Suenkel , Pablo Porras , Rebekka Migotti , Franziska Schmidt , Melanie Kny , Xiaoxi Zhu , Erich E Wanker , Gunnar Dittmar , Jens Fielitz , Thomas Sommer	2019-09-06	-
30745168	POH1 contributes to hyperactivation of TGF-Î² signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-Î² receptors and caveolin-1. EBioMedicine Boshi Wang , Xiaoli Xu , Zhaojuan Yang , Li Zhang , Yun Liu , Aihui Ma , Guiqin Xu , Ming Tang , Tiantian Jing , Lin Wu , Yongzhong Liu	2019-03-01	-
28536997	PLXNA3 Variant rs5945430 is Associated with Severe Clinical Course in Male Multiple Sclerosis Patients. Neuromolecular Med. Moaz Qureshi , Mohamed Hatem , Raed Alroughani , Sindhu P Jacob , Rabeah Abbas Al-Temaimi	2017-09-01	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26496610	A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , JÃ¼rgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , JÃ¶rg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann	2015-10-22	Cep85l, Rcc1, Zbtb48, Bsdc1, Kifc1, Ccp110, Ints4, Slc6a8, Cenpi, Nup107, Xpo1, Fbxw11, Tubg1, Csnk1d, Bap1, Ptpn23, Tecpr2, Slain1, Ankrd28, Prkaa1, Espl1, Gbf1, Cdc20, Cenpf, Trip11, Mbd5, Kif22, Dut, Srsf1, Actb, Spred2, Akt2, Mta1, Tgs1, Pip4k2c, Ankfy1, Apc, Ar, Rhoa, Atp2a2, Atp5a1, Atp7a, Cep131, Bach1, Bcl7c, Bmpr1a, Brca1, Bub1, Bub1b, C1qbp, Anxa2, Calu, Cbx1, Cbx4, Cct2, Cct3, Cct4, Cct7, Cct8, Cd2ap, Cdk1, Cdc37, Cdh1, Chek1, Cit, Copa, Crebbp, Cry1, Csk, Smc3, Dctn1, Ddb1, Cdk2ap1, Mapre1, Ect2, Eef1a1, Eif3a, Mark2, Evpl, Ewsr1, Wdr5, Dclre1b, Fbl, Fgfr1, Flot1, Flot2, B4galt1, Gnb1, Gspt1, Hdac6, Herc2, Hsf1, Hsph1, Elavl1, Id2, Cyr61, Cep250, Insr, Eif3e
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
25518740	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure. J. Hum. Genet. Michel Belyk , Shelly Jo Kraft , Steven Brown , Pediatric Imaging, Neurocognition and Genetics Study	2015-03-01	-
22199357	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein. J Biol Chem Xiangbing Meng , Danlin Zhu , Shujie Yang , Xinjun Wang , Zhi Xiong , Yuping Zhang , Pavla Brachova , Kimberly K Leslie	2012-02-10	-
21925246	Semaphorin-plexin signalling genes associated with human breast tumourigenesis. Gene P N Gabrovska , R A Smith , T Tiang , S R Weinstein , L M Haupt , L R Griffiths	2011-12-10	SEMA4F, SEMA4D, PLXNA2, PLXNA3
21900206	A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker	2011-09-06	KCNE3, HDAC6, PDCD6IP, ZNF605, TOM1L1, HMGXB4, RANBP9, RWDD2B, SNUPN, TSSC4, ARPC3, ACTR1B, CDH13, CEBPZ, RBM5, CDK4, CDK5, TRIM13, EIF1, DDX39A, HNRNPR, RABEPK, SPRY2, CDKN1A, CDK2AP2, LOC400927-CSNK1E, RGS19, CDKN2B, DSCR3, IKZF1, NPM3, TUBA1B, TUBB3, RACK1, PIAS3, NDC80, YAP1, CDIPT, TUBGCP3, TIMM17A, TAB1, FST, STK25, DEAF1, KAT5, GLRX3, DCTN2, PRDX4, RABAC1, DPYSL4, CCT7, CCT4, DRAP1, CENPB, TXNIP, NPRL2, GNB5, CERS1, CFL1, MGEA5, PLK4, RAI1, GIPC1, ZNF266, UTP14A, PGRMC1, RAB10, YIF1A, JTB, GADD45G, AFG3L2, C11orf58, HNRNPA0, PNRC1, ADIRF, COPS6, IMMT, SF3B2, KIF2C, RAB31, ADAP1, PIM2, RCC1, NUDT21, SNRNP35, CHD3, STMN2, HSF2BP, SPACA9, RPP14, FGFR1OP, FAF1, ZWINT, CHGA, CDC37, CHGB, KAT7, C14orf1, NUDT5

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