| Type | Description |
|---|---|
| Definition | tripartite motif containing 36 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:34:00 | TRIM36 is a novel androgen-responsive gene, and it dramatically enhanced the efficacy of anti-androgen drugs against prostate cancer. | 29449534 |
| 2019-01-05 10:45:00 | Results suggest that high expression of TRIM36 is associated with favorable prognosis and that TRIM36 plays a tumor-suppressive role by inhibiting cell proliferation and migration as well as promoting apoptosis in prostate cancer. | 30238687 |
| 2017-07-29 12:54:00 | aberrant hypermethylation of TRIM36 might be involved in the acquisition of malignant phenotype and could be served as a biomarker for risk assessment of PAHs exposure | 28359976 |
| 2017-05-20 12:27:00 | The siRNA knock down of TRIM36 in HeLa and LN229 cells also led to reduced cell proliferation and increased apoptosis. We suggest that microtubule disruption and disorganized spindles mediated by mutant TRIM36 affect neural cell proliferation during neural tube formation, leading to Anencephaly . | 28087737 |
| 2017-02-17 08:27:00 | TRIM36 is the causative gene for autosomal recessive anencephaly | 28087737 |
| Type | IDs |
|---|---|
| Synonymous | ANPH, HAPRIN, RBCC728, RNF98 |
| Gene |
UniProtKB-ID:
TRI36_HUMAN,
E9PBG3_HUMAN,
Q4R1Q4_HUMAN
UniprotKB:
Q9NQ86,
E9PBG3,
Q4R1Q4
UniParc:
UPI000013DCD9,
UPI0001D3B644,
UPI0000509F0B,
UPI000020C435,
UPI000052FE9F,
UPI000020C438
EMBL:
BX460627,
AC094104,
BC045164,
AK296389,
CH471086,
AC008494,
AJ272269,
AB196558,
AK316422,
BC046096,
KC877071,
BC130334
Ensembl:
ENSG00000152503
KO:
hsa:55521
|
| Nucleutide sequences |
EMBL-CDS:
AAH45164.1,
BAH12340.1,
AAI30335.1,
EAW48972.1,
AAH46096.1,
BAH14793.1,
CAB94831.1,
BAD99605.1
Ensembl_TRS:
ENST00000513154,
ENST00000379618,
ENST00000282369,
ENST00000379617,
ENST00000514154
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368938,
ENSP00000423934,
ENSP00000282369,
ENSP00000368937,
ENSP00000424259
RefSeq:
XP_016865110.1,
NP_061170.2,
XP_016865112.1,
NP_001017397.1,
XP_016865111.1,
NP_001017398.1,
NP_001287688.1,
NP_001287681.1
|
| Others |
UniRef100:
UniRef100_E9PBG3,
UniRef100_Q9NQ86,
UniRef100_Q4R1Q4
UniRef90:
UniRef90_Q4R1Q4,
UniRef90_Q9NQ86,
UniRef90_A0A5F4CQI0
UniRef50:
UniRef50_Q9NQ86,
UniRef50_H2PGA8,
UniRef50_A0A5F4BY74
UniGene:
Hs.519514,
Hs.638953
CCDS:
CCDS4115.1,
CCDS34212.1,
CCDS34211.1,
CCDS75287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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