| Type | Description |
|---|---|
| Definition | DEAD-box helicase 43 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:31:00 | DDX43 prefers single-strand DNA or RNA with length longer than 12nt and much prefers guanosine than the other three nucleotides. Achievement of the full binding affinity of protein to substrate needs the existence of all domains, and they must be connected. The absence of either of them or the disjunction can result in a decreased binding affinity to substrates, approximately reduced 10-fold. | 31623828 |
| 2019-08-17 10:32:00 | DDX43 is highly expressed in lung adenocarcinoma, and the expression level is related to the stage and metastasis of lung adenocarcinoma. | 29044003 |
| 2019-03-16 12:07:00 | DDX43 provides critical support to the progression of chronic myeloid leukemia (CML) by enhancing cell survival, colony formation, and inhibiting cell apoptosis, thereby implicating DDX43 as a potential therapeutic target in CML. | 29449695 |
| 2017-07-08 12:42:00 | results demonstrate that DDX43 is a dual helicase and the KH domain is required for its full unwinding activity. | 28468824 |
| 2016-11-05 11:31:00 | HAGE expression is a potential prognostic marker and a predictor of response to anthracycline treatment in triple negative breast cancer. | 26240276 |
| Type | IDs |
|---|---|
| Synonymous | CT13, HAGE |
| Gene |
UniProtKB-ID:
DDX43_HUMAN
UniprotKB:
Q9NXZ2
UniParc:
UPI00017A8499,
UPI000013CA60
EMBL:
BC066938,
AC019205,
AJ278110,
AK303324,
AL136751
Ensembl:
ENSG00000080007
KO:
hsa:55510
|
| Nucleutide sequences |
EMBL-CDS:
CAB92442.1,
AAH66938.1,
BAG64390.1,
CAB66685.1
Ensembl_TRS:
ENST00000370336
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359361
RefSeq:
NP_061135.2
|
| Others |
UniRef100:
UniRef100_Q9NXZ2
UniRef90:
UniRef90_Q9NXZ2
UniRef50:
UniRef50_Q9NXZ2
UniGene:
Hs.125507
CCDS:
CCDS4977.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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