| Type | Description |
|---|---|
| Definition | hes family bHLH transcription factor 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 10:47:00 | High HES6 expression is associated with metastasis in colorectal cancer. | 30015909 |
| 2016-04-02 11:47:00 | prostate cancer-specific up-regulation of NOTCH3 and HES6, is reported. | 25864518 |
| 2015-05-23 12:11:00 | HES6 mutations are associated with castration resistant and androgen independent tumors in prostate cancer. | 25006183 |
| 2014-12-27 12:13:00 | HES6 is up-regulated in aggressive human prostate cancer and drives tumour growth by enhancing the transcriptional activity of the AR, which is preferentially directed to a regulatory network enriched for transcription factors such as E2F1. | 24737870 |
| 2013-01-26 10:19:00 | HES6 contributes to the pathogenesis of alveolar rhabdomyosarcoma by enhancing both proliferation and cell motility. | 22982728 |
| Type | IDs |
|---|---|
| Synonymous | C-HAIRY1, HES-6, bHLHb41, bHLHc23 |
| Gene |
UniProtKB-ID:
HES6_HUMAN
UniprotKB:
Q96HZ4
UniParc:
UPI00000719E1,
UPI0001881A05,
UPI00000720F7,
UPI000006FA86
EMBL:
AK075040,
AK293111,
CH471063,
AC016757,
AB035179,
BC007939,
AF260237
Ensembl:
ENSG00000144485
KO:
hsa:55502
|
| Nucleutide sequences |
EMBL-CDS:
BAA96082.1,
AAH07939.1,
AAY24337.1,
AAK51634.1,
BAC11368.1,
EAW71151.1,
BAF85800.1
Ensembl_TRS:
ENST00000409160,
ENST00000409574,
ENST00000272937,
ENST00000409002
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000387215,
ENSP00000387155,
ENSP00000272937,
ENSP00000387008
RefSeq:
NP_061115.2,
NP_001136325.1,
NP_001269363.1
|
| Others |
UniRef100:
UniRef100_Q96HZ4
UniRef90:
UniRef90_Q96HZ4
UniRef50:
UniRef50_Q9JHE6
UniGene:
Hs.42949
CCDS:
CCDS2527.1,
CCDS63180.1,
CCDS46556.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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