| Type | Description |
|---|---|
| Definition | proline and arginine rich end leucine rich repeat protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:43:00 | A novel biomarker of MMP-cleaved prolargin is elevated in patients with psoriatic arthritis. | 32782251 |
| 2018-09-01 12:12:00 | Up regulation of prolargin in RA suggests the likelihood of an adaptive mechanism to control the increased osteoclastogenesis in RA and may have therapeutic value in controlling the disease. | 29402456 |
| 2017-11-25 14:02:00 | PRELP was more expressed in peritoneal lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue. | 28678915 |
| 2017-09-16 11:20:00 | this study shows that PRELP enhances host innate immunity against Moraxella catarrhalis through increasing complement-mediated attack, improving phagocytic killing activity of neutrophils, and preventing bacterial adherence to lung epithelial cells | 28148731 |
| 2017-06-10 10:29:00 | These findings provide support for a role of the N-terminal region of PRELP as an important regulator of cell adhesion and behaviour, which may be of importance in pathological conditions. | 26920026 |
| Type | IDs |
|---|---|
| Synonymous | MST161, MSTP161, SLRR2A |
| Gene |
UniProtKB-ID:
PRELP_HUMAN
UniprotKB:
P51888
UniParc:
UPI000013222E
EMBL:
BC032498,
U41344,
CH471067,
U29089,
AL391817,
CR542270,
U41343
Ensembl:
ENSG00000188783
KO:
hsa:5549
|
| Nucleutide sequences |
EMBL-CDS:
AAC50230.1,
CAG47066.1,
AAH32498.1,
EAW91481.1,
AAC18782.1
Ensembl_TRS:
ENST00000343110
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343924
RefSeq:
NP_002716.1,
NP_958505.1
|
| Others |
UniRef100:
UniRef100_P51888
UniRef90:
UniRef90_P51888
UniRef50:
UniRef50_P51888
UniGene:
Hs.632481
CCDS:
CCDS1438.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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