| Type | Description |
|---|---|
| Definition | neuropeptide Y receptor Y4 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 10:06:00 | Our results suggest that NPY4R genetic variation influences body weight in women, but the exact role of this receptor appears to be more complex than previously proposed. | 29621259 |
| 2017-12-02 11:06:00 | the internalization motif for the human neuropeptide Y4 receptor, which regulates arrestin-3 recruitment and receptor endocytosis, was identified. | 27818291 |
| 2016-12-17 12:06:00 | A copy number variation (CNV) analysis demonstrated a significantly higher frequency of NPY4R containing 10q11.22 CNV loss in the patient population, while CNV gain in this region was more prevalent in the control population. Mutation analysis resulted in the identification of 15 rare non-synonymous heterozygous variants. Two variants in the patient population demonstrated receptor dysfunction and a pathogenic effect. | 26921218 |
| 2016-11-05 10:17:00 | Data suggest that repression of JNK-c-Jun signaling through pancreatic polypeptide receptor 1 (PP1) is one of the key anti-tumor mechanisms of neuronal membrane cytoskeletal protein 4.1 (4.1N). | 26575790 |
| 2015-03-21 10:35:00 | These data demonstrate glucose-regulated secretion of PP and its effects on glucagon release through PPYR1 receptors expressed by alpha-cells. | 25445712 |
| Type | IDs |
|---|---|
| Synonymous | NPY4-R, PP1, PPYR1, Y4 |
| Gene |
UniProtKB-ID:
NPY4R_HUMAN
UniprotKB:
P50391
UniParc:
UPI0000050415
EMBL:
AY649986,
BC096238,
CR541950,
U35232,
Z66526,
AY268432,
U42387,
AY649985,
AL390716
Ensembl:
ENSG00000204174
KO:
hsa:5540,
hsa:100996758
|
| Nucleutide sequences |
EMBL-CDS:
AAC50280.1,
CAI13318.1,
AAP23199.1,
AAV68197.1,
AAV68196.1,
AAH96238.1,
CAA91433.1,
CAG46748.1,
AAB07759.1
Ensembl_TRS:
ENST00000395716,
ENST00000374312,
ENST00000612632
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480883,
ENSP00000363431,
ENSP00000379066
RefSeq:
XP_016871875.1,
XP_016871876.1,
NP_005963.4,
NP_001265723.1,
XP_011538238.1,
XP_011538239.1
|
| Others |
UniRef100:
UniRef100_P0DQD5
UniRef90:
UniRef90_P0DQD5
UniRef50:
UniRef50_Q63447
UniGene:
Hs.524719
CCDS:
CCDS81459.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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