| Type | Description |
|---|---|
| Definition | minichromosome maintenance 10 replication initiation factor |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. | 33712616 |
| 2021-03-20 13:34:00 | MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells. | 33340428 |
| 2021-01-09 13:31:00 | Knockdown of MCM10 Gene Impairs Glioblastoma Migration and Invasion and the Implications for the Regulation of Tumorigenesis. | 32030558 |
| 2020-04-18 11:19:00 | High MCM10 expression is associated with lung adenocarcinoma. | 31545501 |
| 2020-04-04 11:33:00 | MCM10 is highly expressed in lung cancer (LC) clinical specimens and significantly associated with recurrence, pathological stage and worse overall survival. MCM10 knockdown in A549 and H661 cell lines significantly suppressed cell viability, clone formation and induced G1 phase arrest by regulating the expression of CCND1. Results indicated a combined effect of MCM10CCND1 in predicting the prognosis of LC patients. | 31638210 |
| Type | IDs |
|---|---|
| Synonymous | CNA43, DNA43, PRO2249 |
| Gene |
UniProtKB-ID:
MCM10_HUMAN
UniprotKB:
Q7L590
UniParc:
UPI000013C5E2,
UPI0000073D6F
EMBL:
CH471072,
AL138764,
AL136840,
AL355355,
AK055695,
BC101727,
AF119869,
BC143490,
BC004876,
AK292701,
AB042719
Ensembl:
ENSG00000065328
KO:
hsa:55388
|
| Nucleutide sequences |
EMBL-CDS:
CAB66774.2,
AAH04876.2,
BAB18723.1,
AAF69623.1,
EAW86297.1,
AAI43491.1,
AAI01728.1,
BAF85390.1,
BAB70988.1
Gene_ORFName:
PRO2249
Ensembl_TRS:
ENST00000378714,
ENST00000484800
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367986,
ENSP00000418268
RefSeq:
NP_060988.3,
XP_011517840.1,
NP_877428.1
|
| Others |
UniRef100:
UniRef100_Q7L590
UniRef90:
UniRef90_Q7L590
UniRef50:
UniRef50_Q7L590
UniGene:
Hs.198363
CCDS:
CCDS7096.1,
CCDS7095.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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