| Type | Description |
|---|---|
| Definition | palmitoyl-protein thioesterase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:53:00 | High PPT1 expression is associated with cancer. | 30442709 |
| 2019-03-16 13:10:00 | The results demonstrate that these patient iPSC derived NCL NSCs are valid cell- based disease models with characteristic disease phenotypes that can be used for study of disease pathophysiology and drug development. | 29631617 |
| 2019-01-19 11:33:00 | the study contributes four novel variants to the spectrum of PPT1 gene mutations and eight novel variants to the TPP1 gene mutation data in neuronal ceroid lipofuscinoses type I and type II | 30541466 |
| 2018-06-16 11:01:00 | Targeting PPT1 blocks mTOR signaling in a manner distinct from catalytic inhibitors, while concurrently inhibiting autophagy, thereby providing a new strategy for cancer therapy. | 28899863 |
| 2018-01-06 11:35:00 | the combination of elevated glycolysis and deficient MRPL13 activity was closely linked to CLN1-mediated tumor activity in human hepatoma cells | 28978646 |
| Type | IDs |
|---|---|
| Synonymous | CLN1, INCL, PPT |
| Gene |
UniProtKB-ID:
PPT1_HUMAN
UniprotKB:
P50897
UniParc:
UPI00017A80A9,
UPI0000132113
EMBL:
AF022209,
AK312287,
AF022208,
AF022204,
AK302232,
AF022211,
CH471059,
AF022203,
AF022207,
L42809,
CR542053,
BC008426,
U44772,
AL512599,
AF022206,
AF022210,
AF022205
Ensembl:
ENSG00000131238
KO:
hsa:5538
|
| Nucleutide sequences |
EMBL-CDS:
EAX07238.1,
CAG46850.1,
EAX07237.1,
BAG35214.1,
AAB06236.1,
BAG63586.1,
AAA85337.1,
AAH08426.1,
AAB72224.1
Ensembl_TRS:
ENST00000529905,
ENST00000449045,
ENST00000642050
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000432053,
ENSP00000493153,
ENSP00000392293
RefSeq:
NP_000301.1,
NP_001136076.1,
NP_001350624.1
|
| Others |
UniRef100:
UniRef100_P50897
UniRef90:
UniRef90_P50897
UniRef50:
UniRef50_P50897
UniGene:
Hs.3873
CCDS:
CCDS44119.1,
CCDS447.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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