| Type | Description |
|---|---|
| Definition | leucine rich repeat containing 59 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. | 31068071 |
| 2019-05-04 10:14:00 | the mechanisms of membrane integration of LRRC59 and its targeting to the inner nuclear membrane (INM), were investigated. | 30650545 |
| 2016-02-27 11:40:00 | Endosomal localization of endogenous TLR3 was decreased by silencing of LRRC59, suggesting that LRRC59 promotes UNC93B1-mediated translocation of NA-sensing TLRs from the ER upon infection. | 26466955 |
| 2015-11-21 11:57:00 | we provide a novel therapeutic mechanism for inhibiting CIP2A function in cancerous cells via targeting the CIP2A-LRRC59 interaction. | 25833693 |
| 2012-08-18 11:02:00 | LRRC59 facilitates transport of cytosolic FGF1 through nuclear pores by interaction with Kpns and movement of LRRC59 along the ER and NE membranes | 22321063 |
| Type | IDs |
|---|---|
| Synonymous | PRO1855, p34 |
| Gene |
UniProtKB-ID:
LRC59_HUMAN
UniprotKB:
Q96AG4
UniParc:
UPI0000071220
EMBL:
CH471109,
AF119857,
AK316593,
BC052279,
BC017168
Ensembl:
ENSG00000108829
KO:
hsa:55379
|
| Nucleutide sequences |
EMBL-CDS:
AAH17168.1,
AAF69611.1,
EAW94615.1,
BAG38180.1,
AAH52279.1,
EAW94616.1
Gene_ORFName:
PRO1855
Ensembl_TRS:
ENST00000225972
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225972
RefSeq:
NP_060979.2
|
| Others |
UniRef100:
UniRef100_Q96AG4
UniRef90:
UniRef90_Q96AG4
UniRef50:
UniRef50_Q96AG4
UniGene:
Hs.370927
CCDS:
CCDS11566.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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