| Type | Description |
|---|---|
| Definition | leucine rich repeat containing G protein-coupled receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:22:00 | Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia. | 32559496 |
| 2021-02-06 13:53:00 | LGR4 overexpression is associated with clinical parameters and poor prognosis of serous ovarian cancer. | 32176632 |
| 2021-02-06 13:51:00 | Ablation of LGR4 signaling enhances radiation sensitivity of prostate cancer cells. | 33171177 |
| 2020-10-03 12:58:00 | Association between LGR4 polymorphisms and peak bone mineral density and body composition. | 32399675 |
| 2020-01-25 13:16:00 | MicroRNA-34a negatively controls LGR4, thereby inhibiting the migration and invasion of uveal melanoma cells. Ultimately, both miR-34a and LGR4 impact the aggressiveness of uveal melanoma with alterations in the markers of the epithelial-mesenchymal transition. | 31661551 |
| Type | IDs |
|---|---|
| Synonymous | BNMD17, GPR48 |
| Gene |
UniProtKB-ID:
LGR4_HUMAN,
Q59ER8_HUMAN
UniprotKB:
Q9BXB1,
Q59ER8
UniParc:
UPI00004F6DFF,
UPI00000373E7,
UPI0000E5931B
EMBL:
AF346709,
AF346710,
CH471064,
AC090597,
BC033039,
AB209743,
AC100771,
AF346711,
AF257182
Ensembl:
ENSG00000205213
KO:
hsa:55366
|
| Nucleutide sequences |
EMBL-CDS:
AAF68989.1,
AAK31153.1,
EAW68286.1,
EAW68285.1,
AAH33039.1,
BAD92980.1
Ensembl_TRS:
ENST00000379214,
ENST00000389858
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000374508,
ENSP00000368516
RefSeq:
NP_060960.2,
NP_001333361.1
|
| Others |
UniRef100:
UniRef100_Q9BXB1
UniRef90:
UniRef90_Q9BXB1
UniRef50:
UniRef50_A2ARI4
UniGene:
Hs.502176
CCDS:
CCDS31449.1,
CCDS86187.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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