| Type | Description |
|---|---|
| Definition | serine/threonine/tyrosine kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:59:00 | SMAD3 induces the transcription of STYK1 to promote epithelial-mesenchymal transition and to elicit paclitaxel resistance of ovarian cancer cells. | 30701575 |
| 2020-07-11 10:25:00 | elevated serine threonine tyrosine kinase 1 (STYK1) or decreased serine peptidase inhibitor Kunitz type 2 (SPINT2/HAI-2) expression significantly correlated with poor prognosis, tumor invasion, and metastasis of NSCLC patients. STYK1 overexpression promoted NSCLC cells proliferation, migration, and invasion. STYK1 also induced epithelial-mesenchymal transition by E-cadherin downregulation and Snail upregulation. | 31164631 |
| 2020-06-27 10:10:00 | Data suggest that regulating ferroptosis could be another cancerous mechanism of serine/threonine/tyrosine kinase 1 (STYK1). | 31542233 |
| 2019-01-19 11:49:00 | findings suggest that STYK1 is a critical regulator of tumor growth and metastasis. | 29413947 |
| 2018-06-02 11:15:00 | Overexpression of STYK1 was significantly associated with increased cell proliferation, migratory capability, and invasive capability in vitro, as well as increased volume of tumor, weight of tumor, and number of pulmonary metastasesin hepatocellular carcinoma. | 27628214 |
| Type | IDs |
|---|---|
| Synonymous | NOK, SuRTK106 |
| Gene |
UniProtKB-ID:
STYK1_HUMAN
UniprotKB:
Q6J9G0
UniParc:
UPI000013C57C
EMBL:
BC093822,
AL353940,
CH471094,
BC093824,
AC021049,
AK313906,
AF251059,
AY563054
Ensembl:
ENSG00000060140
KO:
hsa:55359
|
| Nucleutide sequences |
EMBL-CDS:
AAH93822.1,
BAG36629.1,
AAT01226.1,
AAK34949.1,
CAB89250.1,
EAW96200.1,
AAH93824.1
Ensembl_TRS:
ENST00000075503
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000075503
RefSeq:
XP_011519040.1,
XP_016875068.1,
NP_060893.2,
XP_011519038.1,
XP_005253474.1,
XP_011519039.1
|
| Others |
UniRef100:
UniRef100_Q6J9G0
UniRef90:
UniRef90_Q6J9G0
UniRef50:
UniRef50_Q6J9G0
UniGene:
Hs.24979
CCDS:
CCDS8629.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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