| Type | Description |
|---|---|
| Definition | lysosomal protein transmembrane 4 beta |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Overexpression of LAPTM4B-35 is a negative prognostic factor in head and neck squamous cell carcinoma. | 31827181 |
| 2020-11-21 13:34:00 | Lysosome Associated Protein Transmembrane 4B-24 Is the Predominant Protein Isoform in Human Tissues and Undergoes Rapid, Nutrient-Regulated Turnover. | 32679228 |
| 2020-06-20 11:11:00 | Epithelial-to-mesenchymal transition in Gastric Cancer is promoted by a combination of LAPTM4B overexpression and H. pylori infection. | 31084933 |
| 2019-11-23 10:35:00 | Lysosome-associated transmembrane protein 4B (LAPTM4B) is overexpressed in triple-negative breast cancer. The knockdown of LAPTM4B restores cyclin-dependent kinase inhibitor p27 (p27kip1) expression and inhibits the aggressiveness of breast cancer cells. | 31033460 |
| 2019-11-02 10:54:00 | In the current study, we performed a meta-analysis to find out the exact role of LAPTM4B polymorphism on risk of cancer. The results revealed that LAPTM4B polymorphism significantly increased the risk of cancer in codominant, dominant, overdominant, and allele genetic inheritance models | 30255662 |
| Type | IDs |
|---|---|
| Synonymous | LAPTM4beta, LC27 |
| Gene |
UniProtKB-ID:
LAP4B_HUMAN
UniprotKB:
Q86VI4
UniParc:
UPI000018F5E2,
UPI00000377AE
EMBL:
BC031021,
AL136942,
AF527412,
AF317417,
BC038117,
AK075326,
AY261384,
AY057051,
BC014129
Ensembl:
ENSG00000104341
KO:
hsa:55353
|
| Nucleutide sequences |
EMBL-CDS:
AAL17908.2,
AAH31021.1,
BAC11549.1,
AAK69595.1,
CAB66876.2,
AAH14129.1,
AAO84265.1,
AAP14034.1,
AAH38117.1
Gene_ORFName:
PSEC0001
Ensembl_TRS:
ENST00000521545,
ENST00000445593,
ENST00000619747
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402301,
ENSP00000482533,
ENSP00000428409
RefSeq:
NP_060877.4
|
| Others |
UniRef100:
UniRef100_Q86VI4
UniRef90:
UniRef90_Q86VI4
UniRef50:
UniRef50_Q86VI4
UniGene:
Hs.492314
CCDS:
CCDS6275.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员