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55340 GIMAP5

55340

GIMAP5

GTPase, IMAP family member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition GTPase, IMAP family member 5

研究结论

Date Results Publications
2018-03-31 10:22:00 GIMAP5 loss-of-function mutation results in T cell deficiencies. 29382851
2017-04-15 11:16:00 These data,demonstrating the downregulation of the mRNA and protein expression levels of GIMAP5 and GIMAP6 in the tumor tissues and blood of patients with HCC, suggested the involvement of GIMAP5 and GIMAP6 in the pathogenesis of HCC, and indicate their possible use as diagnostic markers for HCC. 27667392
2016-02-06 11:03:00 gimap5 has a role in maintaining peripheral tolerance and T cell homeostasis in the gut [review] 25944983
2013-03-30 12:18:00 Data indicate that overexpression of GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) in HEK (human embryonic kidney)-293 cells resulted in increased Ca2+ accumulation within the mitochondria. 23098229
2011-01-01 11:14:00 Notch signalling protects T-ALL cells from apoptosis by upregulating the expression of GIMAP5. 20817506

名称对应

Type IDs
Synonymous HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD
Gene
UniProtKB-ID: GIMA5_HUMAN, A0A090N8P9_HUMAN
UniprotKB: Q96F15, A0A090N8P9
UniParc: UPI000004EC77, UPI0000070F68
EMBL: AACC02000108, CH471173, BC011732, AK055568, AK002158, CR457280
Ensembl: ENSG00000196329
KO: hsa:55340
Nucleutide sequences
EMBL-CDS: BAB70958.1, EAW54092.1, BAA92115.1, AAH11732.1, EAW54094.1, CAG33561.1, EAW54093.1, EAL24486.1
Gene_ORFName: tcag7.771
Ensembl_TRS: ENST00000498181, ENST00000358647
Protein sequencees
Ensembl_PRO: ENSP00000487840, ENSP00000351473
RefSeq: NP_060854.2
Others
UniRef100: UniRef100_Q96F15
UniRef90: UniRef90_Q96F15
UniRef50: UniRef50_Q96F15
UniGene: Hs.647079, Hs.698139
CCDS: CCDS5907.1

全选

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