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55332 DRAM1

55332

DRAM1

DNA damage regulated autophagy modulator 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition DNA damage regulated autophagy modulator 1

研究结论

Date Results Publications
2020-09-12 16:01:00 DRAM1 deficiency affects the organization and function of the Golgi apparatus. 31356858
2020-06-27 10:07:00 The expression of serum DRAM1 messenger RNA (mRNA), ARSA mRNA, hsa-miR-2053 and lncRNA-RP1-86D1.3 were positive in 78.3%, 90%, 85%, and 83.3% of MPM patients, respectively. 30362153
2020-02-22 10:30:00 DRAM-1 binds the membrane carrier protein SCAMP3 and the amino acid transporters SLC1A5 and LAT1, directing them to lysosomes and permitting efficient mTORC1 activation. 31492633
2019-10-26 12:54:00 Our results indicated that DRAM1 protected cardiomyocytes from ischemia stress-induced autophagy flux obstacle and uncovered a novel DRAM1-Atg7-Atg12/Atg5 autophagy flux regulation pathway under conditions of myocardial ischemic stress. 30144448
2019-08-17 12:10:00 these results identify that the class I PI3K-Akt-rpS6 pathway is regulated by DRAM1 and may provide new insight into the potential role of DRAM1 in human cancers. 30902093

名称对应

Type IDs
Synonymous DRAM
Gene
UniProtKB-ID: DRAM1_HUMAN, A0A024RBF9_HUMAN
UniprotKB: Q8N682, A0A024RBF9
UniParc: UPI00000733DA, UPI0001914F96
EMBL: AC063950, AC084398, BC013773, AK297785, CH471054, BC018435, AC079907, AK002121
Ensembl: ENSG00000136048
KO: hsa:55332
Nucleutide sequences
EMBL-CDS: BAH12666.1, BAA92091.1, AAH18435.1, AAH13773.4, EAW97685.1, EAW97686.1
Gene_ORFName: hCG_1782034
Ensembl_TRS: ENST00000544152, ENST00000258534
Protein sequencees
Ensembl_PRO: ENSP00000258534, ENSP00000445827
RefSeq: XP_016875067.1, XP_005269062.1, NP_060840.2, XP_005269061.1
Others
UniRef100: UniRef100_Q8N682
UniRef90: UniRef90_Q8N682
UniRef50: UniRef50_Q8N682
UniGene: Hs.525634
CCDS: CCDS41823.1

全选

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研究热度

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