| Type | Description |
|---|---|
| Definition | alkaline ceramidase 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 11:57:00 | Our study suggests that Acer3 contributes to hepatocellular carcinoma propagation | 30097213 |
| 2017-11-04 11:20:00 | Homozygosity for the p.E33G mutation in the ACER3 gene results in inactivation of ACER3. | 26792856 |
| 2017-06-03 10:50:00 | The ACER3 deficiency resulted in decreased cell growth and colony formation, elevated apoptosis, and lower AKT signaling of leukemia cells. This study indicates that ACER3 contributes to AML pathogenesis, and suggests that alkaline ceramidase inhibition is an option to treat acute myeloid leukemia. | 27470583 |
| 2010-09-15 22:07:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-09-15 22:07:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Synonymous | APHC, PHCA, PLDECO |
| Gene |
UniProtKB-ID:
ACER3_HUMAN,
B7Z2V2_HUMAN,
B7Z2Q2_HUMAN
UniprotKB:
Q9NUN7,
B7Z2V2,
B7Z2Q2
UniParc:
UPI0001914C2A,
UPI000013DB7C,
UPI000015F407,
UPI0001914B75
EMBL:
KF455419,
BC073853,
KC877444,
AF327353,
AK316120,
CH471076,
AK295142,
AK294978,
AF214454,
AK002100,
AK315000,
AP003119,
AP002498,
AP000752
Ensembl:
ENSG00000078124
KO:
hsa:55331
|
| Nucleutide sequences |
EMBL-CDS:
BAA92085.1,
AAL56013.1,
AAH73853.1,
BAG37496.1,
EAW75010.1,
AAK71923.1,
BAH14491.1,
BAH11988.1,
BAH11938.1
Ensembl_TRS:
ENST00000532485,
ENST00000526597,
ENST00000533873
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434480,
ENSP00000431149,
ENSP00000436252
RefSeq:
NP_060837.3,
XP_011543454.1,
NP_001287882.1,
NP_001287883.1,
XP_011543453.1,
XP_016873477.1,
XP_011543455.1,
NP_001287884.1,
XP_016873476.1
|
| Others |
UniRef100:
UniRef100_B7Z2Q2,
UniRef100_Q9NUN7
UniRef90:
UniRef90_Q9NUN7,
UniRef90_A0A452EC46
UniRef50:
UniRef50_Q9D099,
UniRef50_Q9NUN7
UniGene:
Hs.23862
CCDS:
CCDS8247.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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