BLOC1S4 - biogenesis of lysosomal organelles complex 1 subunit 4-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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55330 BLOC1S4

基因描述

Type	Description
Definition	biogenesis of lysosomal organelles complex 1 subunit 4

研究结论

Date	Results	Publications
2012-03-17 11:44:00	Melanoma cells depleted of cappuccino protein have increased nuclear localization of cis-diaminedichloroplatinum II, increased nuclear DNA damage by platination, and increased apoptosis, resulting in increased treatment sensitivity.	22203954

名称对应

Type	IDs
Synonymous	BCAS4L, BLOS4, CNO
Gene	UniProtKB-ID: BL1S4_HUMAN UniprotKB: Q9NUP1 UniParc: UPI0000073D20 EMBL: BC067815, AC093323, BC001818, AK002092, BC009890 Ensembl: ENSG00000186222 KO: hsa:55330
Nucleutide sequences	EMBL-CDS: AAH67815.1, BAA92080.1 Ensembl_TRS: ENST00000320776
Protein sequencees	Ensembl_PRO: ENSP00000318128 RefSeq: NP_060836.1
Others	UniRef100: UniRef100_Q9NUP1 UniRef90: UniRef90_Q9NUP1 UniRef50: UniRef50_Q8VED2 UniGene: Hs.7570 CCDS: CCDS3393.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
26673895	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray KÄ±rlÄ± , Samir Karaca , Heinz JÃ¼rgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk GÃ¶rlich	2015-01-01	CHA1, KRR1, SRO9, STE50, RRP7, RNQ1, DCC1, GBP2, SAT4, RVS161, YCR016W, PWP2, SSK22, SOL2, PAT1, YCR087C-A, OCA4, MOB2, EPL1, BUD27, FRS2, LOC1, YFR016C, LSB3, RPL2A, PHO4, SAP155, IRC6, ENT4, PRP19, RIX7, YLL032C, FRA1, ISA1, SPA2, PUF3, RPL8B, NOC3, SSL1, SSK1, NSE1, RLP24, SDO1, ADE16, RPL15A, STU2, RPS0B, FRS1, BMT6, KIN2, HRT3, REX3, YLR108C, CFT2, MSL5, ACE2, STM1, YLR157C-A, APS1, CBF5, SWI6, SKG3, HCR1, PWP1, NOP56, BUR2, GPN3, DBP9, GCD7, SGD1, STE11, NMD4, RPS22B, ROM2, STP3, IKI3, REH1, AFG2, UTP21, ATG17, TUS1, MAG2, ATG23, RPS1A, FPR4, PDP3, CDC24, RBG1, FUN12, MTW1, PRP45, MAK16, ECM1, GPB2, VPS8, KIN3, CDC15, YAT1, WHI4
22203680	Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem Hyung Ho Lee , Daniel Nemecek , Christina Schindler , William J Smith , Rodolfo Ghirlando , Alasdair C Steven , Juan S Bonifacino , James H Hurley	2012-02-17	-
22203954	Targeting protein-trafficking pathways alters melanoma treatment sensitivity. Proc. Natl. Acad. Sci. U.S.A. Zhi-ming Huang , Milka Chinen , Philip J Chang , Tong Xie , Lily Zhong , Stephanie Demetriou , Mira P Patel , Rebecca Scherzer , Elena V Sviderskaya , Dorothy C Bennett , Glenn L Millhauser , Dennis H Oh , James E Cleaver , Maria L Wei	2012-01-10	-
21900206	A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker	2011-09-06	KCNE3, HDAC6, PDCD6IP, ZNF605, TOM1L1, HMGXB4, RANBP9, RWDD2B, SNUPN, TSSC4, ARPC3, ACTR1B, CDH13, CEBPZ, RBM5, CDK4, CDK5, TRIM13, EIF1, DDX39A, HNRNPR, RABEPK, SPRY2, CDKN1A, CDK2AP2, LOC400927-CSNK1E, RGS19, CDKN2B, DSCR3, IKZF1, NPM3, TUBA1B, TUBB3, RACK1, PIAS3, NDC80, YAP1, CDIPT, TUBGCP3, TIMM17A, TAB1, FST, STK25, DEAF1, KAT5, GLRX3, DCTN2, PRDX4, RABAC1, DPYSL4, CCT7, CCT4, DRAP1, CENPB, TXNIP, NPRL2, GNB5, CERS1, CFL1, MGEA5, PLK4, RAI1, GIPC1, ZNF266, UTP14A, PGRMC1, RAB10, YIF1A, JTB, GADD45G, AFG3L2, C11orf58, HNRNPA0, PNRC1, ADIRF, COPS6, IMMT, SF3B2, KIF2C, RAB31, ADAP1, PIM2, RCC1, NUDT21, SNRNP35, CHD3, STMN2, HSF2BP, SPACA9, RPP14, FGFR1OP, FAF1, ZWINT, CHGA, CDC37, CHGB, KAT7, C14orf1, NUDT5
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7
15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem Marta Starcevic , Esteban C Dell'Angelica	2004-07-02	-
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano	2004-01-01	Slc9a8, Nefm, Hfe2, AKT3, ZBTB11-AS1, LOC100034248, PDZK1P1, DDTL, LOC100049716, ACOT8, GNPDA1, ZBTB33, GTF2IP4, POM121C, ZSCAN30, SRA1, SNORD123, UCKL1-AS1, ZGLP1, LOC100125918, LINC00322, LOC100127940, HECW1-IT1, LOC100127955, LOC100127972, LOC100127974, FAM229A, LOC100128076, STAU2-AS1, LOC100128164, TMPO-AS1, LOC100128219, LOC100128239, LOC100128253, TNK2-AS1, DNM1P35, LOC100128288, DLG5-AS1, LOC100128310, TRAPPC3L, FAM83H-AS1, LOC100128361, LOC100128364, FAM225B, LOC100128386, LOC100128398, ASTN2-AS1, C1orf132, MYHAS, LOC100128651, LINC00476, SRRM2-AS1, GPR158-AS1, LINC01165, VPS9D1-AS1, FAM66B, GATA6-AS1, LINC01310, LOC100128979, LOC100128988, LOC100129034, SEMA3F-AS1, UNQ6494, LOC100129115, KHDC1L, LOC100129175, MATN1-AS1, SLC39A12-AS1, LOC100129297, LOC100129312, LINC00484, LOC100129397, LOC100129406, DDC-AS1, LOC100129434, LOC100129447, LOC100129455, LYRM4-AS1, ZNF37BP, LOC100129516, LOC100129518, LOC100129540, LOC100129572, FAM47E, LOC100129620, LOC100129648, C9orf173-AS1, LOC100129775, SLC25A21-AS1, PCOLCE-AS1, SCOC-AS1, LOC100129884, LOC100129894, LOC100129917, LOC100129935, LOC100130078, LOC100130111, MAPT-IT1, MIR124-2HG

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