| Type | Description |
|---|---|
| Definition | serine palmitoyltransferase long chain base subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 10:17:00 | This study demonstrated that the association of SPTLC3insACAC (p = 0.055) with the treatment-resistant ophthalmoplegic subphenotype of myasthenia gravis. | 28673556 |
| 2017-05-20 10:36:00 | The association between the SPTLC3 rs364585 SNP and serum total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels in the Han and Jing populations | 28056980 |
| 2016-05-14 11:47:00 | Data identified LC3B globular structures in esophageal adenocarcinoma patients strongly associated with patient outcome irrespective of treatment. | 26265176 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| Type | IDs |
|---|---|
| Synonymous | C20orf38, LCB 3, LCB2B, LCB3, SPT 3, SPT3, SPTLC2L, dJ718P11, dJ718P11.1, hLCB2b |
| Gene |
UniProtKB-ID:
SPTC3_HUMAN
UniprotKB:
Q9NUV7
UniParc:
UPI0000D6BFB5,
UPI000013E9C7
EMBL:
BC150644,
BC005205,
AL109983,
AK001974,
AL133331,
BC020656,
AL445589,
AL050320
Ensembl:
ENSG00000172296
KO:
hsa:55304
|
| Nucleutide sequences |
EMBL-CDS:
CAM13116.1,
CAM27358.1,
AAI50645.1,
CAM16427.1,
AAH05205.1,
BAA92012.1,
AAH20656.1,
CAM28300.1
Ensembl_TRS:
ENST00000399002
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000381968
RefSeq:
XP_011527581.1,
XP_011527582.1,
NP_001336874.1,
NP_060797.2,
XP_016883411.1
|
| Others |
UniRef100:
UniRef100_Q9NUV7
UniRef90:
UniRef90_Q9NUV7
UniRef50:
UniRef50_Q9NUV7
UniGene:
Hs.425023
CCDS:
CCDS13115.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28673556 |
Neuromuscul. Disord. Melissa Nel , Mahjoubeh Jalali Sefid Dashti , Junaid Gamieldien , Jeannine M Heckmann |
2017-09-01 | - |
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 28056980 |
Lipids Health Dis Qing-Hui Zhang , Rui-Xing Yin , Hui Gao , Feng Huang , Jin-Zhen Wu , Shang-Ling Pan , Wei-Xiong Lin , De-Zhai Yang |
2017-01-05 | - |
| 25378659 |
Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res Rozenn N Lemaitre , Irena B King , Edmond K Kabagambe , Jason H Y Wu , Barbara McKnight , Ani Manichaikul , Weihua Guan , Qi Sun , Daniel I Chasman , Millennia Foy , Lu Wang , Jingwen Zhu , David S Siscovick , Michael Y Tsai , Donna K Arnett , Bruce M Psaty , Luc Djousse , Yii-Der I Chen , Weihong Tang , Lu-Chen Weng , Hongyu Wu , Majken K Jensen , Audrey Y Chu , David R Jacobs , Stephen S Rich , Dariush Mozaffarian , Lyn Steffen , Eric B Rimm , Frank B Hu , Paul M Ridker , Myriam Fornage , Yechiel Friedlander |
2015-01-01 | - |
| 26265176 |
LC3B globular structures correlate with survival in esophageal adenocarcinoma. BMC Cancer Shereen El-Mashed , Tracey R O'Donovan , Elaine W Kay , Ayat R Abdallah , Mary-Clare Cathcart , Jacintha O'Sullivan , Anthony O'Grady , John Reynolds , Seamus O'Reilly , Gerald C O'Sullivan , Sharon L McKenna |
2015-01-01 |
SPTLC3
|
| 24816252 |
An atlas of genetic influences on human blood metabolites. Nat. Genet. So-Youn Shin , Eric B Fauman , Ann-Kristin Petersen , Jan Krumsiek , Rita Santos , Jie Huang , Matthias Arnold , Idil Erte , Vincenzo Forgetta , Tsun-Po Yang , Klaudia Walter , Cristina Menni , Lu Chen , Louella Vasquez , Ana M Valdes , Craig L Hyde , Vicky Wang , Daniel Ziemek , Phoebe Roberts , Li Xi , Elin Grundberg , Multiple Tissue Human Expression Resource (MuTHER) Consortium , Melanie Waldenberger , J Brent Richards , Robert P Mohney , Michael V Milburn , Sally L John , Jeff Trimmer , Fabian J Theis , John P Overington , Karsten Suhre , M Julia Brosnan , Christian Gieger , Gabi Kastenmüller , Tim D Spector , Nicole Soranzo |
2014-06-01 | - |
| 24097068 |
Discovery and refinement of loci associated with lipid levels. Nat. Genet. Cristen J Willer , Ellen M Schmidt , Sebanti Sengupta , Gina M Peloso , Stefan Gustafsson , Stavroula Kanoni , Andrea Ganna , Jin Chen , Martin L Buchkovich , Samia Mora , Jacques S Beckmann , Jennifer L Bragg-Gresham , Hsing-Yi Chang , AyÅe Demirkan , Heleen M Den Hertog , Ron Do , Louise A Donnelly , Georg B Ehret , Tõnu Esko , Mary F Feitosa , Teresa Ferreira , Krista Fischer , Pierre Fontanillas , Ross M Fraser , Daniel F Freitag , Deepti Gurdasani , Kauko Heikkilä , Elina Hyppönen , Aaron Isaacs , Anne U Jackson , à sa Johansson , Toby Johnson , Marika Kaakinen , Johannes Kettunen , Marcus E Kleber , Xiaohui Li , Jian'an Luan , Leo-Pekka Lyytikäinen , Patrik K E Magnusson , Massimo Mangino , Evelin Mihailov , May E Montasser , Martina Müller-Nurasyid , Ilja M Nolte , Jeffrey R O'Connell , Cameron D Palmer , Markus Perola , Ann-Kristin Petersen , Serena Sanna , Richa Saxena , Susan K Service , Sonia Shah , Dmitry Shungin , Carlo Sidore , Ci Song , Rona J Strawbridge , Ida Surakka , Toshiko Tanaka , Tanya M Teslovich , Gudmar Thorleifsson , Evita G Van den Herik , Benjamin F Voight , Kelly A Volcik , Lindsay L Waite , Andrew Wong , Ying Wu , Weihua Zhang , Devin Absher , Gershim Asiki , Inês Barroso , Latonya F Been , Jennifer L Bolton , Lori L Bonnycastle , Paolo Brambilla , Mary S Burnett , Giancarlo Cesana , Maria Dimitriou , Alex S F Doney , Angela Döring , Paul Elliott , Stephen E Epstein , Gudmundur Ingi Eyjolfsson , Bruna Gigante , Mark O Goodarzi , Harald Grallert , Martha L Gravito , Christopher J Groves , Göran Hallmans , Anna-Liisa Hartikainen , Caroline Hayward , Dena Hernandez , Andrew A Hicks , Hilma Holm , Yi-Jen Hung , Thomas Illig , Michelle R Jones , Pontiano Kaleebu , John J P Kastelein , Kay-Tee Khaw , Eric Kim , Norman Klopp , Pirjo Komulainen , Meena Kumari , Claudia Langenberg , Terho Lehtimäki , Shih-Yi Lin , Jaana Lindström , Ruth J F Loos , François Mach , Wendy L McArdle , Christa Meisinger , Braxton D Mitchell , Gabrielle Müller , Ramaiah Nagaraja , Narisu Narisu , Tuomo V M Nieminen , Rebecca N Nsubuga , Isleifur Olafsson , Ken K Ong , Aarno Palotie , Theodore Papamarkou , Cristina Pomilla , Anneli Pouta , Daniel J Rader , Muredach P Reilly , Paul M Ridker , Fernando Rivadeneira , Igor Rudan , Aimo Ruokonen , Nilesh Samani , Hubert Scharnagl , Janet Seeley , Kaisa Silander , Alena StanÄáková , Kathleen Stirrups , Amy J Swift , Laurence Tiret , Andre G Uitterlinden , L Joost van Pelt , Sailaja Vedantam , Nicholas Wainwright , Cisca Wijmenga , Sarah H Wild , Gonneke Willemsen , Tom Wilsgaard , James F Wilson , Elizabeth H Young , Jing Hua Zhao , Linda S Adair , Dominique Arveiler , Themistocles L Assimes , Stefania Bandinelli , Franklyn Bennett , Murielle Bochud , Bernhard O Boehm , Dorret I Boomsma , Ingrid B Borecki , Stefan R Bornstein , Pascal Bovet , Michel Burnier , Harry Campbell , Aravinda Chakravarti , John C Chambers , Yii-Der Ida Chen , Francis S Collins , Richard S Cooper , John Danesh , George Dedoussis , Ulf de Faire , Alan B Feranil , Jean Ferrières , Luigi Ferrucci , Nelson B Freimer , Christian Gieger , Leif C Groop , Vilmundur Gudnason , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Aroon Hingorani , Joel N Hirschhorn , Albert Hofman , G Kees Hovingh , Chao Agnes Hsiung , Steve E Humphries , Steven C Hunt , Kristian Hveem , Carlos Iribarren , Marjo-Riitta Järvelin , Antti Jula , Mika Kähönen , Jaakko Kaprio , Antero Kesäniemi , Mika Kivimaki , Jaspal S Kooner , Peter J Koudstaal , Ronald M Krauss , Diana Kuh , Johanna Kuusisto , Kirsten O Kyvik , Markku Laakso , Timo A Lakka , Lars Lind , Cecilia M Lindgren , Nicholas G Martin , Winfried März , Mark I McCarthy , Colin A McKenzie , Pierre Meneton , Andres Metspalu , Leena Moilanen , Andrew D Morris , Patricia B Munroe , Inger Njølstad , Nancy L Pedersen , Chris Power , Peter P Pramstaller , Jackie F Price , Bruce M Psaty , Thomas Quertermous , Rainer Rauramaa , Danish Saleheen , Veikko Salomaa , Dharambir K Sanghera , Jouko Saramies , Peter E H Schwarz , Wayne H-H Sheu , Alan R Shuldiner , Agneta Siegbahn , Tim D Spector , Kari Stefansson , David P Strachan , Bamidele O Tayo , Elena Tremoli , Jaakko Tuomilehto , Matti Uusitupa , Cornelia M van Duijn , Peter Vollenweider , Lars Wallentin , Nicholas J Wareham , John B Whitfield , Bruce H R Wolffenbuttel , Jose M Ordovas , Eric Boerwinkle , Colin N A Palmer , Unnur Thorsteinsdottir , Daniel I Chasman , Jerome I Rotter , Paul W Franks , Samuli Ripatti , L Adrienne Cupples , Manjinder S Sandhu , Stephen S Rich , Michael Boehnke , Panos Deloukas , Sekar Kathiresan , Karen L Mohlke , Erik Ingelsson , Gonçalo R Abecasis , Global Lipids Genetics Consortium |
2013-11-01 | - |
| 23192594 |
Hum. Genet. Digna R Velez Edwards , Adam C Naj , Keri Monda , Kari E North , Marian Neuhouser , Oyunbileg Magvanjav , Ibukun Kusimo , Mara Z Vitolins , Joann E Manson , Mary Jo O'Sullivan , Evadnie Rampersaud , Todd L Edwards |
2013-03-01 |
LOC100128373,
LOC101929231,
ZPLD1,
LOC152225,
MOSPD2,
DCC,
PA2G4P2,
SLC39A11,
DICER1,
FRZB,
CNTNAP2,
RPL15P2,
LOC347097,
LOC359819,
CDK4PS,
LOC400750,
BCAM,
MGMT,
NTRK2,
DNAJC10,
POU3F1,
SPTLC3,
SEPT11,
PELI2,
NECTIN2,
SLC28A3,
DIO3OS,
SGK1,
LRP8,
ZNF385D,
PIP5K1B,
MAML2,
CNTNAP1,
ITGBL1,
KCNE2
|
| 22359512 |
PLoS Genet AyÅe Demirkan , Cornelia M van Duijn , Peter Ugocsai , Aaron Isaacs , Peter P Pramstaller , Gerhard Liebisch , James F Wilson , Ã sa Johansson , Igor Rudan , Yurii S Aulchenko , Anatoly V Kirichenko , A Cecile J W Janssens , Ritsert C Jansen , Carsten Gnewuch , Francisco S Domingues , Cristian Pattaro , Sarah H Wild , Inger Jonasson , Ozren Polasek , Irina V Zorkoltseva , Albert Hofman , Lennart C Karssen , Maksim Struchalin , James Floyd , Wilmar Igl , Zrinka Biloglav , Linda Broer , Arne Pfeufer , Irene Pichler , Susan Campbell , Ghazal Zaboli , Ivana Kolcic , Fernando Rivadeneira , Jennifer Huffman , Nicholas D Hastie , Andre Uitterlinden , Lude Franke , Christopher S Franklin , Veronique Vitart , DIAGRAM Consortium , Christopher P Nelson , Michael Preuss , CARDIoGRAM Consortium , Joshua C Bis , Christopher J O'Donnell , Nora Franceschini , CHARGE Consortium , Jacqueline C M Witteman , Tatiana Axenovich , Ben A Oostra , Thomas Meitinger , Andrew A Hicks , Caroline Hayward , Alan F Wright , Ulf Gyllensten , Harry Campbell , Gerd Schmitz , EUROSPAN consortium |
2012-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员