Type | Description |
---|---|
Definition | GTPase, IMAP family member 4 |
Date | Results | Publications |
---|---|---|
2015-12-19 12:04:00 | GIMAP4 regulates secretion of cytokines in early differentiating human CD4(+) T helper lymphocytes and in particular the secretion of interferon-gamma also affecting its downstream targets. | 25287446 |
2013-10-19 10:27:00 | Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease | 23041938 |
2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
2010-01-21 00:00:00 | GIMAP1 and GIMAP4 genes are up-regulated by IL-12 and other Th1 differentiation-inducing cytokines in cells induced to differentiate toward Th1 lineage and down-regulated by IL-4 in cells induced to Th2. | 18701445 |
2010-01-21 00:00:00 | molecular and genetic properties; expression in resting T- and B-cells and decreased expression during lymphocyte activation | 11964296 |
Type | IDs |
---|---|
Synonymous | IAN-1, IAN1, IMAP4, MSTP062 |
Gene |
UniProtKB-ID:
GIMA4_HUMAN,
A0A090N7X0_HUMAN
UniprotKB:
Q9NUV9,
A0A090N7X0
UniParc:
UPI0000073CB0
EMBL:
CH471173,
AACC02000108,
BC020657,
AF117333,
AK001972
Ensembl:
ENSG00000133574
KO:
hsa:55303
|
Nucleutide sequences |
EMBL-CDS:
BAA92010.1,
AAO15308.1,
AAH20657.1,
EAW54104.1,
EAL24482.1
Gene_ORFName:
MSTP062,
hCG_1643312,
tcag7.779
Ensembl_TRS:
ENST00000255945
|
Protein sequencees |
Ensembl_PRO:
ENSP00000255945
RefSeq:
NP_001350461.1,
NP_060796.1
|
Others |
UniRef100:
UniRef100_Q9NUV9
UniRef90:
UniRef90_Q9NUV9
UniRef50:
UniRef50_Q9NUV9
UniGene:
Hs.647101,
Hs.648582
CCDS:
CCDS5904.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
25287446 |
Immunol. Cell Biol. Mirkka T Heinonen , Kartiek Kanduri , Harri J Lähdesmäki , Riitta Lahesmaa , Tiina A Henttinen |
2015-02-01 | - |
23041938 |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease. Ann. Rheum. Dis. Yun Jong Lee , Yukihiro Horie , Graham R Wallace , Yong Seok Choi , Ji Ah Park , Ji Yong Choi , Ran Song , Young-Mo Kang , Seong Wook Kang , Han Joo Baek , Nobuyoshi Kitaichi , Akira Meguro , Nobuhisa Mizuki , Kenichi Namba , Susumu Ishida , Jinhyun Kim , Edyta Niemczyk , Eun Young Lee , Yeong Wook Song , Shigeaki Ohno , Eun Bong Lee |
2013-09-01 |
GIMAP4
|
23454188 |
Structural insights into the mechanism of GTPase activation in the GIMAP family. Structure David Schwefel , B Sivanandam Arasu , Stephen F Marino , Björn Lamprecht , Karl Köchert , Eva Rosenbaum , Jenny Eichhorst , Burkhard Wiesner , Joachim Behlke , Oliver Rocks , Stephan Mathas , Oliver Daumke |
2013-04-02 |
GIMAP8,
GIMAP7,
GIMAP2,
GIMAP6,
GIMAP4
|
21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21244100 |
J. Proteome Res. Dezso P Virok , Dóra Simon , Zsolt Bozsó , Róbert Rajkó , Zsolt Datki , Ãva Bálint , Viktor Szegedi , Tamás Janáky , Botond Penke , LÃvia Fülöp |
2011-04-01 |
FAM27E3,
ADARB1,
SYNCRIP,
MYBBP1A,
RAD51AP1,
CAMKK2,
CELF2,
POLD3,
PTTG2,
UTP14A,
SRSF8,
SF3B2,
KIF2C,
WDR5,
KATNA1,
KIF3A,
AKAP13,
DDX20,
MRPL3,
KLF12,
OSBPL11,
ZNF641,
AEBP2,
MTFMT,
C16orf78,
ZNF684,
TCEANC2,
HMGB4,
C1orf87,
C1orf131,
KCTD18,
SPATA4,
CARNMT1,
RNF32,
CSNK1D,
CSNK1E,
CMTM2,
SYT6,
CTNNA1,
CTNND1,
AIFM3,
DNAJB7,
OR6B3,
ZNF385B,
PP2D1,
CFAP58,
CCDC60,
APOBEC3H,
DDX10,
PRICKLE2,
OLFML2A,
TCEANC,
DNM2,
S1PR1,
AGO4,
EEF1D,
DZIP1L,
ELK1,
TIGD1,
ANKS6,
SUSD3,
ZNF449,
EPB41L2,
ERCC1,
ETV3,
OR4D6,
PATL1,
FES,
FGF12,
FGF13,
ICK,
ZNF365,
TMCC1,
RBM34,
TAB2,
PHF8,
ZC3H3,
RTF1,
ABCF1,
PES1,
PHYHD1,
GABRA4,
C9orf43,
RPL36,
PNKD,
GAPDH,
FAM32A,
DKFZP434K028,
TRAF3IP1,
RSL1D1,
EHF,
AGO1,
OR2W1,
TRMT2A,
RPUSD2,
FILIP1,
TP53TG5,
POLL,
GLRB
|
20237496 |
New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. S Davila , F E M Froeling , A Tan , C Bonnard , G J Boland , H Snippe , M L Hibberd , M Seielstad |
2010-04-01 |
SH2B3,
MICA,
NR1H3,
TSPAN2,
NAMPT,
PRG4,
KLRG1,
CD96,
EFS,
APC2,
LAMC3,
CRISP3,
TLR6,
CLEC10A,
SEMA4D,
CEBPG,
PROCR,
PRDX4,
IFI44,
CXCL13,
GNLY,
COLEC10,
SH2B2,
CD226,
TNFSF13B,
NFAT5,
KLRA1P,
CFHR4,
CFHR3,
C1QL1,
EDAR,
MAGED2,
PRDX3,
IFI44L,
LILRB5,
LILRB4,
LILRA1,
LILRA2,
DUS4L,
ESM1,
FGFR1OP,
FAF1,
CD160,
RASSF1,
IRAK3,
IL17F,
CHRM1,
CD300A,
COPE,
KIF12,
CMTM1,
SIGLEC11,
NLRP3,
TIRAP,
PGLYRP2,
PGLYRP3,
SLAMF6,
FCRL1,
FCRL3,
GBP4,
GBP5,
TNFRSF13C,
FOXP4,
IL22RA2,
DEFB118,
CLC,
ADD1,
SFXN4,
IFI27L1,
CCR3,
CCR4,
CCR5,
CCR7,
CCR8,
ACKR2,
CMKLR1,
CCDC78,
CD300LB,
OSCAR,
ANKLE1,
GABPB2,
CNTFR,
COL4A3,
COL4A4,
BPIFB6,
ZPLD1,
KLF6,
IL31RA,
PPARGC1B,
RAET1E,
ADORA2B,
SSC4D,
CR1,
PXDNL,
CR2,
CREB1,
CREM,
GAB3,
CRP
|
18701445 |
Mol Cell Proteomics Jan-Jonas Filén , Sanna Filén , Robert Moulder , Soile Tuomela , Helena Ahlfors , Anne West , Petri Kouvonen , Suvi Kantola , Mari Björkman , Mikko Katajamaa , Omid Rasool , Tuula A Nyman , Riitta Lahesmaa |
2009-01-01 | - |
18029348 |
Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics Laurent Barbe , Emma Lundberg , Per Oksvold , Anna Stenius , Erland Lewin , Erik Björling , Anna Asplund , Fredrik Pontén , Hjalmar Brismar , Mathias Uhlén , Helene Andersson-Svahn |
2008-03-01 | - |
17207965 |
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics Philippe Lamesch , Ning Li , Stuart Milstein , Changyu Fan , Tong Hao , Gabor Szabo , Zhenjun Hu , Kavitha Venkatesan , Graeme Bethel , Paul Martin , Jane Rogers , Stephanie Lawlor , Stuart McLaren , Amélie Dricot , Heather Borick , Michael E Cusick , Jean Vandenhaute , Ian Dunham , David E Hill , Marc Vidal |
2007-03-01 |
GNPDA1,
CTAGE4,
BCL2L11,
PIGK,
TIMM23,
NPIPA5,
CST8,
AP1M2,
COX17,
TIMM23B,
SNX29P1,
IL18BP,
RWDD2B,
TSSC4,
UPK1A-AS1,
ARPC5,
ARPC3,
TSPAN5,
TSPAN3,
TSPAN1,
PPIF,
CTDSP2,
NAMPT,
PDZK1IP1,
DHRS9,
RBM7,
MPHOSPH6,
DHRS2,
MPZL2,
GPA33,
CALCOCO2,
SPRY3,
SPRY1,
RAMP3,
TRAIP,
DNAJA2,
IKZF1,
CRISP3,
SIRPB1,
CNPY2,
B3GNT3,
WARS2,
NPM3,
CDO1,
CACNG3,
TUBB4B,
CEPT1,
PEMT,
WFDC2,
NSA2,
EMG1,
TIMM17A,
PPIE,
HAX1,
CIB2,
DCTN2,
RPP38,
SLC35A1,
IFI44,
CXCL13,
SIVA1,
MRPL28,
CENPA,
MAB21L2,
RAD51AP1,
MTX2,
CGRRF1,
DCTN6,
B3GNT2,
CLDN16,
PNMA2,
KLRA1P,
SRSF10,
ARPP21,
STARD10,
CGA,
EDDM3A,
CFHR3,
GPR83,
RAB10,
CPSF4,
RUNDC3A,
COPS8,
C11orf58,
CCDC85B,
GLIPR1,
KLK11,
SNRNP27,
LIAS,
LILRA2,
SNRNP35,
CYB561D2,
ESM1,
WDR5,
BTN2A1,
HHLA3,
BVES,
KLK8,
MRPL3
|
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