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55300 PI4K2B

55300

PI4K2B

phosphatidylinositol 4-kinase type 2 beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphatidylinositol 4-kinase type 2 beta

研究结论

Date Results Publications
2017-08-05 12:39:00 RNA interference of the type II phosphatidylinositol 4-kinases PI4KIIa and PI4KIIa in primary human endothelial cells leads to formation of an increased proportion of short WPB with perturbed packing of VWF, as exemplified by increased exposure of antibody-binding sites. 27068535
2016-04-23 11:54:00 Here two crystal structures are presented: the structure of human PIK42A and the structure of PIK42B containing a nucleoside analogue. 26143926
2015-10-31 11:11:00 Results provide evidence that type II PtdIns 4-kinase b was indeed recruited to CD4- p56lck complex upon CD4 receptor cross linking, suggests a mechanism for its association and a role for it in CD4-mediated intracellular calcium release. 24972704
2014-12-06 11:27:00 Canonical tyrosine residues mutation in FcepsilonRIgamma ITAM (Y65 and Y76) reveals that these two tyrosine residues in gamma subunit are required for its interaction with type II PtdIns 4-kinases. 24481753
2014-02-01 10:08:00 type II PtdIns 4-kinase beta is a key component in early T cell activation signaling cascades 23619705

名称对应

Type IDs
Synonymous PI4KIIB, PIK42B
Gene
UniProtKB-ID: P4K2B_HUMAN, G5E9Z4_HUMAN
UniprotKB: Q8TCG2, G5E9Z4
UniParc: UPI000020BDD5, UPI000006DEFC
EMBL: AY091514, CH471069, AF411320, AY065990, AC108218, AK001967, AC104662, BC051749
Ensembl: ENSG00000038210
KO: hsa:55300
Nucleutide sequences
EMBL-CDS: AAL47580.1, BAA92006.1, AAL04154.1, AAH51749.1, AAM12049.1, EAW92836.1
Gene_ORFName: hCG_19614
Ensembl_TRS: ENST00000264864, ENST00000512921
Protein sequencees
Ensembl_PRO: ENSP00000264864, ENSP00000423373
RefSeq: XP_005248232.1, XP_005248231.1, NP_060793.2
Others
UniRef100: UniRef100_G5E9Z4, UniRef100_Q8TCG2
UniRef90: UniRef90_Q8TCG2
UniRef50: UniRef50_Q8TCG2
UniGene: Hs.191701
CCDS: CCDS3433.1

全选

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