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5530 PPP3CA

5530

PPP3CA

protein phosphatase 3 catalytic subunit alpha

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein phosphatase 3 catalytic subunit alpha

研究结论

Date Results Publications
2020-11-21 13:15:00 Differential protein expression of versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder. 31619735
2020-07-04 12:54:00 Calcineurin functions as a positive and negative modulator of gene transcription. 31415762
2020-05-02 12:26:00 Solution NMR shows that the P84A calcineurin Aalpha mutant exists in two forms, compatible with cis-trans isomers, while the P309A mutant is predominantly in the trans conformation 30536857
2020-03-14 12:56:00 Bmp2 is a downstream target of the calcineurin/NFAT pathway in lung endothelium, potently inhibiting cancer cell growth by stimulating differentiation. 30699351
2020-02-15 13:02:00 Overexpression of a constitutively active PPP3CA form, but not its catalytically inactive counterpart, inhibited HIF activity and expression of HIF target genes but did not affect HIF-1alpha or HIF-2alpha expression 30776328

名称对应

Type IDs
Synonymous ACCIID, CALN, CALNA, CALNA1, CCN1, CNA1, IECEE, IECEE1, PPP2B
Gene
UniProtKB-ID: PP2BA_HUMAN, A0A0S2Z4B5_HUMAN, A0A0S2Z4C6_HUMAN
UniprotKB: Q08209, A0A0S2Z4B5, A0A0S2Z4C6
UniParc: UPI00015E4B28, UPI0000D9B19F, UPI0000110660, UPI00000737BA, UPI0000EA22E1
EMBL: KU178270, AC092671, L14778, BC025714, AP001870, AY904364, AB451338, KU178269, AL353950, AK290532, AP001939, AP001816, EU192653, CH471057, AB451487, EU192652
Ensembl: ENSG00000138814
KO: hsa:5530
Nucleutide sequences
EMBL-CDS: AAH25714.1, CAB89253.1, AAA02631.1, ABW74484.1, EAX06124.1, AAY17314.1, BAG70301.1, ABW74485.1, EAX06125.1, BAF83221.1, BAG70152.1, ALQ33727.1, ALQ33728.1
Ensembl_TRS: ENST00000323055, ENST00000394854, ENST00000394853, ENST00000512215
Protein sequencees
Ensembl_PRO: ENSP00000422781, ENSP00000320580, ENSP00000378323, ENSP00000378322
RefSeq: NP_001124164.1, NP_000935.1, NP_001124163.1, XP_016863854.1, XP_024309895.1
Others
UniRef100: UniRef100_Q5R914, UniRef100_Q08209
UniRef90: UniRef90_Q08209, UniRef90_A0A2Y9ER37
UniRef50: UniRef50_Q08209, UniRef50_P48453-2
UniGene: Hs.435512
CCDS: CCDS34037.1, CCDS47114.1, CCDS47113.1

全选

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